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Does the cost of Imatinib change?


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#1 Dom

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Posted 18 July 2017 - 04:49 PM

In a separate thread, I pointed out that Imatinib (400) in march cost 2073.01 (love that extra penny), and then in April it dropped to 1062.90.  And it has been at 1062.90 ever since.  Theses are the prices from Walmart using Express-Scripts as my Part D.

 

I was on the Medicare.gov site to see if I could get a better deal with an Advantage plan.  And I saw that Express Scripts was giving different numbers.  Now Imatinib (400) starting in August is $9,768.86.  Can this be right?  Or should I assume that Medicare.gov got it wrong?

 

And a second question:  Can you change part D plans in mid-year, or is there a special time for that?  Because if Express-scripts is not charging close to $10,000 for imatinib, I want something else.


Diagnosed in February 2014. Started Imatinib 400 in April.
2014:     3.18     0.91
2015:     0.22     0.16     0.04     0.55
2016:     0.71     0.66

(Started Imatinib 600 in April 2016)
2016:     0.42     0.13     0.45
2017:     0.17     0.06     0.10     0.06     0.34


#2 Buzzm1

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Posted 18 July 2017 - 05:50 PM

Dom, from your previous posting:

 

Imatinib 400 (30 pills)       1914.17        976.23

Imatinib 100 (60 pills)       1062.90        416.71
(For April)                                           1392.94


For the benefit of yourself and others please add your CML history into your Signature

 

02/2010 Gleevec 400mg

2011 Two weakly positives, PCRU, weakly positive

2012 PCRU, PCRU, PCRU, PCRU

2013 PCRU, PCRU, PCRU, weakly positive

2014 PCRU, PCRU, PCRU, PCRU (12/07 began dose reduction w/each continuing PCRU)

2015 300, 250, 200, 150

2016 100, 50/100, 100, 10/17 TFR

2017 01/17 TFR, 04/18 TFR, 07/18 TFR 0.0012, 08/29 TFR 0.001, 10/17 TFR 0.000

2018 01/16 TFR 0.0004 ... next quarterly PCR 04/17

 

At the earliest opportunity, and whenever possible, lower your TKI dosage; TKIs are toxic drugs and the less we take longterm the better off we are going to be ... this is especially true for older adults.  

 

In hindsight I should have started my dosage reduction two years earlier; it might have helped minimize some of the longterm cumulative toxic effects of TKIs that I am beset with.  

 

longterm side-effects Peripheral Artery Disease - legs (it's a bitch); continuing shoulder problems, right elbow inflammation.   GFR and creatinine vastly improved after stopping Gleevec.

 

Cumulative Gleevec dosage estimated at 830 grams

 

Taking Gleevec 400mg an hour after my largest meal of the day helped eliminate the nausea that Gleevec is notorious for.  

 

Trey's CML BlogStopping - The OddsStop Studies - Discussion Forum Cessation Study

Big PhRMA - Medicare Status - Social Security Status - Deficit/Debt


#3 Dom

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Posted 18 July 2017 - 06:49 PM

Yes, I got the 100s and the 400s mixed up. So really, the price went from 2073 to 1914. And it has stayed at 1914. Now Medicare is giving the cost at nearly 10,000. And my co-pay went from about 210 to about 850. So I still have the original question. Did the price change or did Medicare get it wrong?

Diagnosed in February 2014. Started Imatinib 400 in April.
2014:     3.18     0.91
2015:     0.22     0.16     0.04     0.55
2016:     0.71     0.66

(Started Imatinib 600 in April 2016)
2016:     0.42     0.13     0.45
2017:     0.17     0.06     0.10     0.06     0.34


#4 Buzzm1

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Posted 18 July 2017 - 07:01 PM

Dom, if you are out of the donut hole, your monthly copay should be 5% of  (1914.17 + 1062.90) = $148.85

 

If not, something has gone wrong.

 

I think the numbers you are getting out of Medicare.gov are as if you are just joining Medicare, and beginning the Rx.  


For the benefit of yourself and others please add your CML history into your Signature

 

02/2010 Gleevec 400mg

2011 Two weakly positives, PCRU, weakly positive

2012 PCRU, PCRU, PCRU, PCRU

2013 PCRU, PCRU, PCRU, weakly positive

2014 PCRU, PCRU, PCRU, PCRU (12/07 began dose reduction w/each continuing PCRU)

2015 300, 250, 200, 150

2016 100, 50/100, 100, 10/17 TFR

2017 01/17 TFR, 04/18 TFR, 07/18 TFR 0.0012, 08/29 TFR 0.001, 10/17 TFR 0.000

2018 01/16 TFR 0.0004 ... next quarterly PCR 04/17

 

At the earliest opportunity, and whenever possible, lower your TKI dosage; TKIs are toxic drugs and the less we take longterm the better off we are going to be ... this is especially true for older adults.  

 

In hindsight I should have started my dosage reduction two years earlier; it might have helped minimize some of the longterm cumulative toxic effects of TKIs that I am beset with.  

 

longterm side-effects Peripheral Artery Disease - legs (it's a bitch); continuing shoulder problems, right elbow inflammation.   GFR and creatinine vastly improved after stopping Gleevec.

 

Cumulative Gleevec dosage estimated at 830 grams

 

Taking Gleevec 400mg an hour after my largest meal of the day helped eliminate the nausea that Gleevec is notorious for.  

 

Trey's CML BlogStopping - The OddsStop Studies - Discussion Forum Cessation Study

Big PhRMA - Medicare Status - Social Security Status - Deficit/Debt


#5 chriskuo

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Posted 19 July 2017 - 02:57 AM

Are you comparing generic to generic or is the higher price Gleevec?

The amount you pay depends on the insurance plan, whether you have reached donut hole or catastrophic, and whether the
drug company raised prices mid-year.

#6 Dom

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Posted 19 July 2017 - 10:15 AM

I'm comparing generic prices from Walmart for express scripts part d. Everything is the same. The problem is, when I got express scripts, Medicare said the cost of imatinib was about 2,000. Now they are saying it's 10,000.
That's the raw cost, irrespective of the Medicare phase.

In a few weeks I'll renew. And I'll see what happens. I'm expecting the catastrophic cost to be just 280. Medicare now says it's over 800.

Diagnosed in February 2014. Started Imatinib 400 in April.
2014:     3.18     0.91
2015:     0.22     0.16     0.04     0.55
2016:     0.71     0.66

(Started Imatinib 600 in April 2016)
2016:     0.42     0.13     0.45
2017:     0.17     0.06     0.10     0.06     0.34


#7 Buzzm1

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Posted 19 July 2017 - 10:20 AM

In a few weeks I'll renew. And I'll see what happens. I'm expecting the catastrophic cost to be just 280. Medicare now says it's over 800.

Dom, how much was your July renewal?

 

As I mentioned above, now that you are out of the donut hole, your cost should be 5% of (1914.17 + 1062.90) = $148.85

Why do you think your cost should be $280?


For the benefit of yourself and others please add your CML history into your Signature

 

02/2010 Gleevec 400mg

2011 Two weakly positives, PCRU, weakly positive

2012 PCRU, PCRU, PCRU, PCRU

2013 PCRU, PCRU, PCRU, weakly positive

2014 PCRU, PCRU, PCRU, PCRU (12/07 began dose reduction w/each continuing PCRU)

2015 300, 250, 200, 150

2016 100, 50/100, 100, 10/17 TFR

2017 01/17 TFR, 04/18 TFR, 07/18 TFR 0.0012, 08/29 TFR 0.001, 10/17 TFR 0.000

2018 01/16 TFR 0.0004 ... next quarterly PCR 04/17

 

At the earliest opportunity, and whenever possible, lower your TKI dosage; TKIs are toxic drugs and the less we take longterm the better off we are going to be ... this is especially true for older adults.  

 

In hindsight I should have started my dosage reduction two years earlier; it might have helped minimize some of the longterm cumulative toxic effects of TKIs that I am beset with.  

 

longterm side-effects Peripheral Artery Disease - legs (it's a bitch); continuing shoulder problems, right elbow inflammation.   GFR and creatinine vastly improved after stopping Gleevec.

 

Cumulative Gleevec dosage estimated at 830 grams

 

Taking Gleevec 400mg an hour after my largest meal of the day helped eliminate the nausea that Gleevec is notorious for.  

 

Trey's CML BlogStopping - The OddsStop Studies - Discussion Forum Cessation Study

Big PhRMA - Medicare Status - Social Security Status - Deficit/Debt


#8 Dom

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Posted 19 July 2017 - 10:48 AM

Because I have a lot of other medication. BP, related heart, cholesterol. But you're right, now that I think of it. The 280 was based on the cost of imatinib back in march when I got express scripts. It's dropped since then. So your price is probably closer.

Except, of course, that Medicare now claims the cost of imatinib just jumped to 10,000.

Diagnosed in February 2014. Started Imatinib 400 in April.
2014:     3.18     0.91
2015:     0.22     0.16     0.04     0.55
2016:     0.71     0.66

(Started Imatinib 600 in April 2016)
2016:     0.42     0.13     0.45
2017:     0.17     0.06     0.10     0.06     0.34


#9 shweflen

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Posted 19 July 2017 - 08:32 PM

I have Express-Scripts and buy my prescriptions at the local Wal-mart.  The insurance company price I have been shown is $1593.82 for 90 - 100mg imatinib each month of which I pay the percentage dictated by Medicare Part D for a generic drug.  I think, I have seen on the paperwork from the pharmacy accompanying the prescription a notation that says the cash price is something just over $7000.

 

I think you can only change Part D plans from sometime in October thru sometime in early December. 

 

I would assume that the insurance companies negotiate a price for a particular drug for the year before establishing their premiums so I'm not sure why or how it would change.


10/20/2016 BCR-ABL:ABL = 81.622

01/11/2017 BCR-ABL:ABL =   8.028

04/12/2017 BCR-ABL:ABL =   0.157

07/07/2017 BCR-ABL:ABL =   0.000

10/04/2017 BCR-ABL:ABL =   0.041

11/28/2017 BCR-ABL:ABL =   0.000

 

 


#10 Buzzm1

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Posted 19 July 2017 - 08:37 PM

10/20/2016 BCR-ABL:ABL = 81.622

01/11/2017 BCR-ABL:ABL =   8.028

04/12/2017 BCR-ABL:ABL =   0.157

07/07/2017 BCR-ABL:ABL =   0.000

Congratulations on reaching undetectable shweflen


For the benefit of yourself and others please add your CML history into your Signature

 

02/2010 Gleevec 400mg

2011 Two weakly positives, PCRU, weakly positive

2012 PCRU, PCRU, PCRU, PCRU

2013 PCRU, PCRU, PCRU, weakly positive

2014 PCRU, PCRU, PCRU, PCRU (12/07 began dose reduction w/each continuing PCRU)

2015 300, 250, 200, 150

2016 100, 50/100, 100, 10/17 TFR

2017 01/17 TFR, 04/18 TFR, 07/18 TFR 0.0012, 08/29 TFR 0.001, 10/17 TFR 0.000

2018 01/16 TFR 0.0004 ... next quarterly PCR 04/17

 

At the earliest opportunity, and whenever possible, lower your TKI dosage; TKIs are toxic drugs and the less we take longterm the better off we are going to be ... this is especially true for older adults.  

 

In hindsight I should have started my dosage reduction two years earlier; it might have helped minimize some of the longterm cumulative toxic effects of TKIs that I am beset with.  

 

longterm side-effects Peripheral Artery Disease - legs (it's a bitch); continuing shoulder problems, right elbow inflammation.   GFR and creatinine vastly improved after stopping Gleevec.

 

Cumulative Gleevec dosage estimated at 830 grams

 

Taking Gleevec 400mg an hour after my largest meal of the day helped eliminate the nausea that Gleevec is notorious for.  

 

Trey's CML BlogStopping - The OddsStop Studies - Discussion Forum Cessation Study

Big PhRMA - Medicare Status - Social Security Status - Deficit/Debt


#11 Dom

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Posted 19 July 2017 - 09:19 PM

Thanks for the info, shweflen. Your prices compare to mine, except I'm getting imatinib 400, but the prices are not out of line with yours. What bothers me is that, when I returned to the Medicare site to look for supplemental plans, I noticed that everything was different for express scripts compared to the paperwork I printed out back in March.

Maybe you have hit on something though. Maybe my prices, and your prices, are locked in because of when we started Medicare, and what I'm seeing now are the new prices for people who are joining in August. I'll have to see what I pay next month. I hope nothing changes next year -- for you and me.

Diagnosed in February 2014. Started Imatinib 400 in April.
2014:     3.18     0.91
2015:     0.22     0.16     0.04     0.55
2016:     0.71     0.66

(Started Imatinib 600 in April 2016)
2016:     0.42     0.13     0.45
2017:     0.17     0.06     0.10     0.06     0.34


#12 chriskuo

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Posted 19 July 2017 - 09:23 PM

My cost for Bosulif went up about 5% mid-year

#13 cmljax

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Posted 20 July 2017 - 06:49 AM

Same for Tasigna - up 5% at mid-year


Dx 9/26/16 WBC 28800; platelets 749; FISH 97% PCR 43%

Tasigna 600MG per day

October 2016                     PCR 22% IS

November 2016                 PCR 5.8% IS

December 2016                 PCR 0.1% IS  MMR!!

March 10, 2017                 PCR 0.006% IS  MR 4.22

Tasigna 450MG per day

April 5, 2017                      PCR <.003% IS

June 5, 2017                     PCR <.003% IS (dose reduction validated!!!)

Tasigna 300MG per day starting June 15, 2017

6-day drug break starting June 20, 2017 due to multiple AE's

July 24, 2017                     PCR <.003% IS

September 18, 2017          Negative, AKA PCRU

Tasigna 150mg per day starting 9/18/17

October 30, 2017               Negative

December 11, 2017           Negative


#14 shweflen

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Posted 20 July 2017 - 09:23 AM

I have Express-Scripts and buy my prescriptions at the local Wal-mart.  The insurance company price I have been shown is $1593.82 for 90 - 100mg imatinib each month of which I pay the percentage dictated by Medicare Part D for a generic drug.  I think, I have seen on the paperwork from the pharmacy accompanying the prescription a notation that says the cash price is something just over $7000.

 

I think you can only change Part D plans from sometime in October thru sometime in early December. 

 

I would assume that the insurance companies negotiate a price for a particular drug for the year before establishing their premiums so I'm not sure why or how it would change.

Now that I think about it, I wonder how the insurance company negotiates prices.  Before I selected Express-Scripts last fall I checked their prices through their captive mail order pharmacy and the prices at their "preferred" provider, Walgreen, and both were much higher than the prices at Wal-mart.


10/20/2016 BCR-ABL:ABL = 81.622

01/11/2017 BCR-ABL:ABL =   8.028

04/12/2017 BCR-ABL:ABL =   0.157

07/07/2017 BCR-ABL:ABL =   0.000

10/04/2017 BCR-ABL:ABL =   0.041

11/28/2017 BCR-ABL:ABL =   0.000

 

 


#15 shweflen

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Posted 20 July 2017 - 09:26 AM

Congratulations on reaching undetectable shweflen

Thank you.  I feel very lucky, minimal side effects and 0's.  My hematologist after getting the latest test results, without prompting from me, said that he had been looking at information about cessation and that we could begin discussing it after an appropriate interval with 0's.


10/20/2016 BCR-ABL:ABL = 81.622

01/11/2017 BCR-ABL:ABL =   8.028

04/12/2017 BCR-ABL:ABL =   0.157

07/07/2017 BCR-ABL:ABL =   0.000

10/04/2017 BCR-ABL:ABL =   0.041

11/28/2017 BCR-ABL:ABL =   0.000

 

 


#16 kat73

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Posted 20 July 2017 - 10:06 AM

Hapy news, Shweflen!


Dx July 2009 on routine physical.  WBC 94.  Started Gleevec 400 mg Sept 2009.  MMR at 2yrs.  Side effects (malaise, depression/anxiety, fatigue, nausea, periorbital edema) never improved.  Kidney issues developed because of Gleevec.  Switched to Sprycel 70 mg in Aug 2011.  Above side effects disappeared or improved.  Have been MR3.5 - 4.5 ever since.  Two untreated pleural effusions followed by one treated by stopping Sprycel Jan 2017.  After 9 weeks, PCR showed loss of MMR; re-started Sprycel at 50 mg and in 3 months was back to <0.01% IS.  Pleural effusion returned within a couple of months, same as before (moderate, left side only).  Stopped Sprycel 50 mg for 12 weeks; pleural effusion resolved.  At about a monthoff the drug, PCR was 0.03; at 11 weeks it was 2.06 - lost CCyR? Have returned to 50 mg Sprycel for 3 weeks, intending to reduce to 20 mg going forward.


#17 Dom

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Posted 20 July 2017 - 12:24 PM

Yes Shweflen, I'm jealous. It happened pretty fast for you too.

Express-scripts still sends me mail asking me to buy my meds through mail order, or at Walgreens, even though the prices are much higher for them and me both.

Diagnosed in February 2014. Started Imatinib 400 in April.
2014:     3.18     0.91
2015:     0.22     0.16     0.04     0.55
2016:     0.71     0.66

(Started Imatinib 600 in April 2016)
2016:     0.42     0.13     0.45
2017:     0.17     0.06     0.10     0.06     0.34


#18 Buzzm1

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Posted 20 July 2017 - 01:03 PM

Thank you.  I feel very lucky, minimal side effects and 0's.  My hematologist after getting the latest test results, without prompting from me, said that he had been looking at information about cessation and that we could begin discussing it after an appropriate interval with 0's.

shweflen, lucky you,  you have a very forward-thinking hematologist.  With your having achieved undetectable in a short time, on only Gleevec 300mg, and considering your age, you are a great candidate for an early attempt at cessation.


For the benefit of yourself and others please add your CML history into your Signature

 

02/2010 Gleevec 400mg

2011 Two weakly positives, PCRU, weakly positive

2012 PCRU, PCRU, PCRU, PCRU

2013 PCRU, PCRU, PCRU, weakly positive

2014 PCRU, PCRU, PCRU, PCRU (12/07 began dose reduction w/each continuing PCRU)

2015 300, 250, 200, 150

2016 100, 50/100, 100, 10/17 TFR

2017 01/17 TFR, 04/18 TFR, 07/18 TFR 0.0012, 08/29 TFR 0.001, 10/17 TFR 0.000

2018 01/16 TFR 0.0004 ... next quarterly PCR 04/17

 

At the earliest opportunity, and whenever possible, lower your TKI dosage; TKIs are toxic drugs and the less we take longterm the better off we are going to be ... this is especially true for older adults.  

 

In hindsight I should have started my dosage reduction two years earlier; it might have helped minimize some of the longterm cumulative toxic effects of TKIs that I am beset with.  

 

longterm side-effects Peripheral Artery Disease - legs (it's a bitch); continuing shoulder problems, right elbow inflammation.   GFR and creatinine vastly improved after stopping Gleevec.

 

Cumulative Gleevec dosage estimated at 830 grams

 

Taking Gleevec 400mg an hour after my largest meal of the day helped eliminate the nausea that Gleevec is notorious for.  

 

Trey's CML BlogStopping - The OddsStop Studies - Discussion Forum Cessation Study

Big PhRMA - Medicare Status - Social Security Status - Deficit/Debt


#19 chriskuo

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Posted 21 July 2017 - 12:30 AM

What kind of insurance do you have that you can choose the supplier? I have options for regular drugs but for
specialty medications, my insurance administrator limits me to its subsidiary which specializes in specialty meds.



#20 Dom

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Posted 21 July 2017 - 08:03 AM

Chriskuo, have express-scripts and so does schwerlen. Are you sure you are limited, or is the insurer just making a strong suggestion? My pre-Medicare insurance didn't make me buy from mail order, but the copays were much cheaper that way.

Diagnosed in February 2014. Started Imatinib 400 in April.
2014:     3.18     0.91
2015:     0.22     0.16     0.04     0.55
2016:     0.71     0.66

(Started Imatinib 600 in April 2016)
2016:     0.42     0.13     0.45
2017:     0.17     0.06     0.10     0.06     0.34





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