After taking Gleevec for 7 months, I switched to Sprycel because of very bad side effects. I have been taking 50 mg of Sprycel for more than 2 years, have been pcru for 15 months, and close to undetectable for 6 months before that. I will soon switch to 40mg(2 20's), with the very reluctant approval of my oncologist. She believes that my having taken 50mg all this time is very unusual--that most people with CML (other than those in clinical trials) are on the "standard" dose of 100mg daily.
I know that many on this board have lowered their dose. I was wondering if there has been any research into how many CMLers have lowered our dosage, how long after diagnosis, how long after attaining pcru(or not), etc.
I know that we are all different, and that what works for one may not work for another. But the blanket statement that the great majority are on 100mg did not seem accurate to me.