Is anyone else having problems with plural effusion caused by Sprycel medication? I started taking Sprycel in March of 2014. I developed breathing problems and started having a Thoracentesis on my right side once a month removing more than 2 liters of fluid each time. We planned our vacation that I would get drained just before leaving. In less than one week I ended up in a hospital to get drained before I could fly back home. They removed 2.5 liters even though I was drained less than a week before. Seeing how I was told I could not fly before getting drained, I think it had to do with the difference in air pressure at altitude.
After returning home, I started having a Thoracentesis on the right and left side every week. In August of 2015, I had a PleurX Catheter inserted in my Right side and began draining 1 liter, 3 times a week and going to the hospital to drain 1+ liter from my Left side once a month. In December of 2015 I had to go to the ER because of dehydration and had to follow up with a Nephrologist. The Nephrologist told me I had to drink at least 2.5 liters of fluid a day; I had to replace what I was removing from my body. In January 2016, I was instructed by my Oncologist to drain 1 liter every day from my right side. Now in May 2016, I was instructed by my Oncologist to stop draining every day and go back to every other day because all of the draining was throwing my electrolytes out of balance. He said at this point it is more a balancing act.
My Oncologist is talking about switching my CML medication. I told him that I have been able to tolerate the side effects of Sprycel and really don't want to change. Is anyone else having problem with plural effusion from other CML targeting medication?