In http://www.medicalne...cles/233878.php "Horwitz said the GATA2 mutations in the DNA sit next to an amino acid that is found to be faulty in some patients with terminal chronic myeloid leukemia."
What is terminal chronic myeloid leukemia? Is it blast crisis? I have never heard CML described like this.
And being "terminal", does that mean a BMT cannot work?
Just wondering. If anyone could explain this, I would be most grateful.
P.S. I would rather play this thing out and try and fail the drugs without knowing I had this gene up front (unless it would determine that I needed a different and available therapy that would work). Hope is a necessity when you have cancer. I also get that this is just what these researchers have found for now and are trying to understand what it fully means. Knowing you carry a deadly gene is no consolation if there is no successful treatment or cure. But I suppose you would not want to pass this to offspring. Nevertheless, it may be rarely inherited. Like, most of the world does not have leukemia. It is still a relatively rare condition, even for the elderly. Sorry, just rambling.