| Event Remark | CBC - No treatment | Suzhuo University first hospital | Start Hydroxyurea | Start Glivec 400mg | Side Effect-Nausea | CHR with myelosuppression WBC < 4 | Side effect-Leg pain | Side effect->Tooth pain and sensitive teeth | leg pain subside | Side effect Dry skin | Side effect Dry skin | Side effect-sometimes hand and leg cramp | CBC and PB RT-PCR => CMR | CBC | ||||
| Date | 28th July 2010 | Aug 6th 2010 | 30/8/10 | 8/9/2010 | 21/9/10 | 30/9/10 | 7/10/2010 | 14/10/10 | 19/10/10 | 26/10/10 | 29/10/10 | 10/11/2010 | 19/10/10 | 23/11/10 | 11/2/2011 | 12/4/2011 | 21/6/11 | 23/8/11 |
| WBC | 29.5 | 29.36 | 31 | 32.6 | 12.4 | 5.8 | 3.6 | 2.4 | 3 | 2.1 | 2.2 | 2.6 | 3 | 2.9 | 2.9 | 2.8 | 4 | 4.6 |
| ANC | 1 | 1.6 | 0.9 | 0.8 | 1.1 | 1.6 | 1.5 | 1.3 | 1.2 | --Err -- | ||||||||
| Hb | 13.1 | 13.3 | 11.5 | 9.8 | 9.9 | 9.6 | 10 | 9.5 | 9.3 | 9.8 | 10.1 | 9.3 | 10.6 | 10.6 | 10.9 | 11 | ||
| Plalete | 1211 | 1181 | 1397 | 1641 | 981 | 428 | 299 | 360 | 370 | 221 | 205 | 273 | 370 | 205 | 323 | 258 | 254 | 273 |
| Lymph | 13.2 | |||||||||||||||||
| Mono | 26.6 | |||||||||||||||||
| IRIS IS PCR scale | 9.26% | 0.00% | ||||||||||||||||
| Molecular Cytogenetic measurement | (b2a2/b3a2)2470/10,000ABL copies. Cytogenetic 46,XY,der(22)t(9:22) | 1,097[BCR-ABL1] copy/ 9594 [ABL1 copies] | 4.5 log reduction. 0[BCR-ABL1] copy/ 51,500 [ABL1 copies] |
Most of my side effect have gone, hopefully the lab Cytogenetic lab report is correct, which means I had achieved CMR after treatment about 9 months.
For side effect like leg pain, subside after about 2 months of treatment.
Dry skin - I use aloe vera gel as treatment. sometime leg skin is very itchy in winter time.
Tooth pain and very sensitive occured during very low ANC, Neutrophil < 1. However this subside after my ANC increased > 1.
