Not easy figuring where to start but....yesterday I had an appointment at Johns Hopkins hospital with Dr. Doug Smith (CML specialist) & Dr. Julia Beaver. To summarize: I started on Gleevec and then switched to Tasigna and have been PCRU for 9 months but my last test indicated a 2 log increase. I have been having other side effects as well. Dr. Doug prescribed a BMB and Kinase Mutation testing (just as our Trey suggested). However, he is very concerned and suggested that based on the next test results I should be considering bone marrow transplant. At 64 years old, I'm sure I want to subject myself to that. The other options would be Sprycel or entering a clinical trial. But he said that since I have not responded well to the first two, any response to another medication would be temporary at best.
Has anyone else here been in the same predicament or offer any suggestions?