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What % is OK?

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#1 WoofWoof


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Posted 16 April 2011 - 07:05 PM

I mentioned before that my last BCR/ABL count showed 1.4% This was a rise from 0% for the last nine months. I will be seeing a CML @ John Hopkins this Thursday.  But in the meantime aside from zero, what percentage is "acceptable"?

I have cancer but it doesn't have me

#2 Trey


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Posted 17 April 2011 - 09:39 AM

Generally, unless the PCR number is very tiny, the PCR number needs to be related to something else -- other PCR numbers or log reductions.  This is because PCR values can vary significantly among labs, especially now that some are International Scale (IS) and some are not.  If your 1.4% is an IS number it is better than if it is on the non-IS scale.  "Acceptable" for most people is a generally declining trend line even though some ups and downs may be seen along the way.  For a person about a year into TKI drug treatment, a 2 log reduction is generally "acceptable".  After a couple years of TKI treatment, a 3 log reduction is generally "acceptable".

In a previous thread I had asked about your PCR history, and that would be helpful for providing a better answer.


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