I am new to the CML world having been diagnosed in 11/10. I am on 400mg Gleevec and have worked hard to remain positive. My regular oncologist sent me to meet with a BMT specialist for a long term treatment plan a couple of months ago. The specialist was the one who told me that I needed to have a PCR test every 90 days and that I needed to achieve a 2 log reduction by 12 months and a 3 log reduction by 18 months. My regular oncologist says my first PCR indicates a 2 log reduction and that I am "just on track". It would seem like I am ahead of schedule and when I asked him, I did not get a straight answer. I am changing oncologists this week because I have a lack of confidence in the current oncologist who appears to lack experience treating CML. I am curious about the milestones a CML patient should achieve. Is a 2 log reduction the goal for one year or is it merely "on track" at 90 days? Trey, you were so helpful with my earlier questions. Any advice would be very much appreciated.