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Gleevec causing heart irregularities? What next?


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#1 Angeelika

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Posted 26 March 2011 - 07:52 PM

My mother has been taking Gleevec for about 5 years now for CML and in the past 2 weeks has suddenly had some pretty significant heart issues.  The beat is very irregular at times and this seems to be happening more often even when she's not active.  I know hear failure is a rare side effect but this has become a major worry of mine.  Has anyone else had issues with taking Gleevec and what if she finds out it is a side effect and she can't take this medication anymore?  What other options are there?  This always seemed like the least complicated medication.

Thank you,

Ang



#2 simone4

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Posted 26 March 2011 - 08:38 PM

I have a history of heart palpitations and irregular heart beats.

She needs to call her oncologist and have an EKG (usually done

in a cardiologist's office). It does not indicate heart failure (that is

Congestive Heart Failure and is different from your mom's symptoms.)

Sometimes just walking around the house or taking a walk around

the block will regulate the heart. Doing it daily is even better.

But I would make sure she has it checked out as soon as possible.

I also take Gleevec and have recently started having the skipped

beats.  I doubt if it is the Gleevec, but  I have an appt. with

my cardiologist next week to check it out.

Good luck to you and your mom.

Simone

Message was edited by: simone4



#3 CallMeLucky

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Posted 26 March 2011 - 09:57 PM

This is very strange this topic came up today, I was just coming on here to look up this issue because Thursday night and now again tonight I am having an issue.  I have been on Gleevec for 9 mo.  I am having the feeling of my heart racing.  My actual pulse seems to be fine and my blood pressure is fine, although slightly elevated for me given where I usually am.  I'm a little perplexed.  I know Thursday was a long day and I wound up at a presentation at 7PM after working allday, the presentation was 90 minutes and when I got there, there were no seats so I stood the whole time.  By the end I started to feel my heart racing.  When I finally sat down it seemed to settle, but stuck with me for a while.  Today was another long day and just a couple of hours ago I started to have the same feeling.  I'm concerned this may be developing into an arrhythmia.  Was curious if anyone else has had this?

I exercise pretty strenuously most days for about an hour in teh morning I never feel a problem them, it is only late in the evening and appears to be after a day where I pushed too far.


Date  -  Lab  -  Scale  -  Drug  -  Dosage MG  - PCR
2010/Jul -  MSKCC  -  Non-IS  -  Gleevec  - 400 - 1.2%
2010/Oct -  MSKCC  -  Non-IS  -  Gleevec  - 400 - 0.25%
2010/Dec -  MSKCC  -  Non-IS  -  Gleevec  - 400 - 0.367%
2011/Mar -  MSKCC  -  Non-IS  -  Gleevec  - 400 - 0.0081%
2011/Jun -  MSKCC  -  Non-IS  -  Gleevec  - 400 - 0%
2011/Sep -  MSKCC  -  Non-IS  -  Gleevec  - 400 - 0.00084%
2011/Dec -  MSKCC  -  Non-IS  -  Gleevec  - 400 - 0%
2012/Mar -  MSKCC  -  Non-IS  -  Gleevec  - 400 - 0.004%
2012/Jun -  MSKCC  -  Non-IS  -  Gleevec  - 400 - 0%
2012/Sep -  MSKCC  -  Non-IS  -  Gleevec  - 400 - 0%
2012/Dec -  MSKCC  -  Non-IS  -  Sprycel  - 100 - 0%
2013/Jan -  Quest  -  IS  -  Sprycel  -  50-60-70  - 0%
2013/Mar -  Quest  -  IS  -  Sprycel  -  60-70  - 0%
2013/Apr -  CUMC  -  Non-IS  -  Sprycel  - 50 - 0.036%
2013/May -  CUMC  -  Non-IS  -  Sprycel  - 50 - 0.046%
2013/Jun -  Genoptix  -  IS  -  Sprycel  - 50 - 0.0239%
2013/Jul -  Genoptix  -  IS  -  Sprycel  - 70 - 0.0192%
2013/Jul -  Genoptix  -  IS  -  Sprycel  - 70 - 0.0034%
2013/Oct -  Genoptix  -  IS  -  Sprycel  - 70 - 0.0054%
2014/Jan -  Genoptix  -  IS  -  Sprycel  - 70 - 0.0093%
2014/Mar -  Genoptix  -  IS  -  Sprycel  - 100 - 0.013%
2014/Apr -  Genoptix  -  IS  -  Sprycel  - 100 - 0.0048%
2014/Jul -  Genoptix  -  IS  -  Sprycel  - 100 - 0%
2014/Nov -  Genoptix  -  IS  -  Sprycel  - 100 - 0.047%
2014/Dec -  Genoptix  -  IS  -  Sprycel  - 100 - 0%
2015/Mar -  Genoptix  -  IS  -  Sprycel  - 100 - 0%
2015/Jun -  Genoptix  -  IS  -  Sprycel  - 100 - 0%
2015/Sep -  Genoptix  -  IS  -  Sprycel  - 100 - 0%
2015/Dec -  Genoptix  -  IS  -  Sprycel  - 100 - 0%
2016/Mar -  Genoptix  -  IS  -  Sprycel  - 100 - 0.0228%
2016/Jun -  Genoptix  -  IS  -  Sprycel  - 100 - 0%
2016/Sep -  Genoptix  -  IS  -  Sprycel  - 100 - 0%
2016/Dec -  Genoptix  -  IS  -  Sprycel  - 100 - 0%
2017/Mar -  Genoptix  -  IS  -  Sprycel  - 100 - 0%
2017/Jun -  Genoptix  -  IS  -  Sprycel  - 100 - 0%
2017/Sep -  Genoptix  -  IS  -  Sprycel  - 100 - 0%
2017/Dec - Genoptix  -  IS  -  Sprycel  -  100 - 0%
 

 


#4 Guest_billronm_*

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Posted 26 March 2011 - 10:23 PM

Hi Lucky,

You still up? I can't sleep. wanna play cards?

                                                                    Billie






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