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How much does stress affect CML


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#1 reedgirl

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Posted 22 February 2011 - 07:30 AM

My husband who I've posted about on here before, diagnosed in July of 2010, has just had his world flipped upside down.  I thought last July was the worst days of my life, undoubtedly they were, but last Thursday we left for a much needed vacation.  We drove 300 miles or so, got a room for the night to then Friday continue our trek to Florida.  At 6 am we received a phone call saying we needed to turn around and come back immediately.  My husband's father who was healthy died in his sleep.  My father in law owned the family business, a hardware store, and was very well known and respected in the community.  My husband worked in that store with his dad since he was quite young and now has the responsibility of taking over, which he is more than able to.  I am just now worried about the stress he will be under dealing with the changes now and settling of his fathers things.  His parents are divorced and his dad remarried with a step son, who was in his teens when they married and never got along with Greg's dad.  Needless to say there will be friction amongst the family when it comes time to take care of things.  Greg has already made comments about not going back to Michigan to see Dr Talpaz, who wanted us to come there so he could treat Greg.

Anyway, enough rambling....I just am worried about the stress and how it may or may not affect Greg

Audrey



#2 hannibellemo

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Posted 22 February 2011 - 12:09 PM

Audrey,

I'm so sorry for your loss!

I'm don't know for sure if stress affects CML or its treatment. I can only say that I achieved MMR in one of the most stressful times of my life. My husband lost his job in a career of over 30 years two weeks before I was diagnosed. One year later his new job was eliminated due to the economy and during that time we were going through a crisis with another family member. Never thought we would be dealing with any of these things and I can definitely say it was extremely difficult.

It made me realize that I am much stronger than I thought I was and it definitely reinforced my belief that we have to be thankful for right now because we are guaranteed no other moment in time!

Good luck to you and your husband in this inevitable, but very sad, transition in your lives!

Pat


Pat

 

"You can't change the direction of the wind but you can adjust your sails."

DX 12/08; Gleevec 400mg; liver toxicity; Sprycel 100mg.; CCyR 4/10; MMR 8/10; Pleural Effusion 2/12; Sprycel 50mg. Maintaining MMR; 2/15 PCRU; 8/16 drifting in and out of undetected like a wave meeting the shore. Retired 12/23/2016! 18 months of PCRU, most recent at Mayo on 7/25/17 was negative at their new sensitivity reporting of 0.003.<p>


#3 Trey

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Posted 22 February 2011 - 06:16 PM

Stress can increase the numbers of white blood cells in some cases.  Your husband could use some more, so maybe it would even be a slightly positive outcome of a very sad event and the fallout you described.

http://www.livestron...te-blood-cells/



#4 Guest_billronm_*

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Posted 22 February 2011 - 08:16 PM

Dear Audrey'

I am so very sorry I want to say something comforting,but I can't think of anything right now. My deepest sympathy to you and Greg. It's amazing just how much the human body can endure, both physically and mentally. Greg will be just fine. You must take care of yourself now. If you need to let it all out just get on this site and vent all you have to.We are all here for you. Our e-mail addresses are not hard to get contact any of us. I will be more than willing to talk to you, I would give you my phone no. via e-mail.I worry so much about what my cml does to  my husband I wish he would talk to someone but he won't. I'll keep both of you in my prayers. Just take a lot of deep breaths it does help.

                                             My deepest sympathy, Billie



#5 Tedsey

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Posted 23 February 2011 - 06:56 PM

Audrey,

I too am very sorry to hear about your loss.  Here is hoping all goes smoothly for you and your husband with as little stress as possible.

Teds   



#6 CallMeLucky

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Posted 23 February 2011 - 09:56 PM

Audrey,

Very sorry to hear about these events.  I don't have much to say in the way of comfort.  My personal thoughts on stress are that they can take a toll on the body physically but from what I have learned about TKI drugs and CML it seems unlikely that stress would inhibit how the drug works at the molecular level.  For myself, I also find that being distracted with things in life, be it good or bad, are often distractions from thinking about CML.

I'll be thinking about you and your husband.....


Date  -  Lab  -  Scale  -  Drug  -  Dosage MG  - PCR
2010/Jul -  MSKCC  -  Non-IS  -  Gleevec  - 400 - 1.2%
2010/Oct -  MSKCC  -  Non-IS  -  Gleevec  - 400 - 0.25%
2010/Dec -  MSKCC  -  Non-IS  -  Gleevec  - 400 - 0.367%
2011/Mar -  MSKCC  -  Non-IS  -  Gleevec  - 400 - 0.0081%
2011/Jun -  MSKCC  -  Non-IS  -  Gleevec  - 400 - 0%
2011/Sep -  MSKCC  -  Non-IS  -  Gleevec  - 400 - 0.00084%
2011/Dec -  MSKCC  -  Non-IS  -  Gleevec  - 400 - 0%
2012/Mar -  MSKCC  -  Non-IS  -  Gleevec  - 400 - 0.004%
2012/Jun -  MSKCC  -  Non-IS  -  Gleevec  - 400 - 0%
2012/Sep -  MSKCC  -  Non-IS  -  Gleevec  - 400 - 0%
2012/Dec -  MSKCC  -  Non-IS  -  Sprycel  - 100 - 0%
2013/Jan -  Quest  -  IS  -  Sprycel  -  50-60-70  - 0%
2013/Mar -  Quest  -  IS  -  Sprycel  -  60-70  - 0%
2013/Apr -  CUMC  -  Non-IS  -  Sprycel  - 50 - 0.036%
2013/May -  CUMC  -  Non-IS  -  Sprycel  - 50 - 0.046%
2013/Jun -  Genoptix  -  IS  -  Sprycel  - 50 - 0.0239%
2013/Jul -  Genoptix  -  IS  -  Sprycel  - 70 - 0.0192%
2013/Jul -  Genoptix  -  IS  -  Sprycel  - 70 - 0.0034%
2013/Oct -  Genoptix  -  IS  -  Sprycel  - 70 - 0.0054%
2014/Jan -  Genoptix  -  IS  -  Sprycel  - 70 - 0.0093%
2014/Mar -  Genoptix  -  IS  -  Sprycel  - 100 - 0.013%
2014/Apr -  Genoptix  -  IS  -  Sprycel  - 100 - 0.0048%
2014/Jul -  Genoptix  -  IS  -  Sprycel  - 100 - 0%
2014/Nov -  Genoptix  -  IS  -  Sprycel  - 100 - 0.047%
2014/Dec -  Genoptix  -  IS  -  Sprycel  - 100 - 0%
2015/Mar -  Genoptix  -  IS  -  Sprycel  - 100 - 0%
2015/Jun -  Genoptix  -  IS  -  Sprycel  - 100 - 0%
2015/Sep -  Genoptix  -  IS  -  Sprycel  - 100 - 0%
2015/Dec -  Genoptix  -  IS  -  Sprycel  - 100 - 0%
2016/Mar -  Genoptix  -  IS  -  Sprycel  - 100 - 0.0228%
2016/Jun -  Genoptix  -  IS  -  Sprycel  - 100 - 0%
2016/Sep -  Genoptix  -  IS  -  Sprycel  - 100 - 0%
2016/Dec -  Genoptix  -  IS  -  Sprycel  - 100 - 0%
2017/Mar -  Genoptix  -  IS  -  Sprycel  - 100 - 0%
2017/Jun -  Genoptix  -  IS  -  Sprycel  - 100 - 0%
2017/Sep -  Genoptix  -  IS  -  Sprycel  - 100 - 0%
2017/Dec - Genoptix  -  IS  -  Sprycel  -  100 - 0%
 

 


#7 Guest_billronm_*

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Posted 28 February 2011 - 01:17 AM

Dear Audrey,

We all hope that things are going as well as possible for you and hubby. I know you have been very busy, we have all been there. Just wanted to let you know we are here for you if you need to vent.You sure do have a lot on your plate right now. It,s amazing how much we can endure when we have to isn,t it?

Sincerely Your many friends from the group.






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