I am so sorry you lost the baby. The one comforting thought may be that from all I heard, it was most likely not to your husband being on Sprycel. I guess miscarriges are more common that we think. But with all that said, it must be hard on you and your husband. But I am sure you will have success in the future.
We have 2 kids already, and while we never thought we'd go for 3, we also didn't want to close that door either. I had been on Sprycel for 3 months, and I wasn't getting any Cytogenetic response (still 17/20), So I looked into the Ariad trial, this was Nov 2009. Part of the trial protocol is that you can't get pregnant on the drug, so in consultation with our doctor I went off Sprycel for 2 weeks prior to starting the Ariad drug, The drug holiday was recommended anyway so that the Sprycel Drug was out of my system before starting Ariad.
We asked our doctor at OHSU and he actually wrote me a note that for medical reasons we wanted to freeze sperm. That helped with the insurance company aspect of it. At the 1 year mark on the trial, I was doing pretty good, 0.0072 at the time, so we decided we wanted to have a 3rd child. Since we already have a 2 and a 4 year old (both boys) I question the sanity of our decision at times.
We went the IVF route, and they put in two eggs, Luckily I guess, 1 egg took and we just had the 12 week sonogram this week, and so far things are still going well. But we did talk to OHSU and also my wife's doctor, to make them aware of the situation. My wife's doctor isn't too concerned about it, and generally the risk is for women per her comment. Anything that can interfere with the growth of the child is of concern.
I was off Sprycel for 2 weeks, but I have also heard that the life cycle of sperm is like 3 months, so that break really didn't do much.
Best wishes, I am sure you'll be just fine and it was unrelated to Sprycel. I know how sensitive we all get on the TKI's, that it's hard to filter out what is TKI related, and what is just life happening.