Posted 18 May 2017 - 07:11 AM
It is a new normal. I went from once a year annual physical, one prescription drug and not so much as a common cold in 10 years to multiple squamous cell skin cancers, irregular heartbeat, mouth sores, swollen salivary glands, GI irregularity, headaches, some fatigue and some insomnia. Many of these side effects have improved and some have completely abated.
I vent all the time to my poor wife, but I also know that the alternative (pre-TKI treatment regimen) was much worse with very poor prognosis. So I try to stay thankful for the TKI even though I hate it a lot of the time. Further dose reduction and maybe even stopping are my goals someday.
Hang in there.
Dx 9/26/16 WBC 28800; platelets 749; FISH 97% PCR 43%
Tasigna 600MG per day
October 2016 PCR 22% IS
November 2016 PCR 5.8% IS
December 2016 PCR 0.1% IS MMR!!
March 10, 2017 PCR 0.006% IS MR 4.22
Tasigna 450MG per day
April 5, 2017 PCR <.003% IS
June 5, 2017 PCR <.003% IS (dose reduction validated!!!)
Tasigna 300MG per day starting June 15, 2017
6-day drug break starting June 20, 2017 due to multiple AE's
July 24, 2017 PCR <.003% IS
September 18, 2017 Negative, AKA PCRU
Tasigna 150mg per day starting 9/18/17
October 30, 2017 Negative
December 11, 2017 Negative