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And now for something completely unexpected ...


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#1 scuba

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Posted 11 February 2017 - 01:02 PM

Drugs that dramatically increase healthy lifespan discovered by Scripps Research, Mayo Clinic March 10, 2015

 

http://www.kurzweila...rch-mayo-clinic

 

https://www.ncbi.nlm...pubmed/26711051

 

Who knew? Seems Dasatinib aka Sprycel exhibits anti-aging properties and may extend lifespan.

Just when I was eager to stop taking Sprycel - maybe taking it is not so bad. I already couple it with Quercetin (taken together just before bedtime).

 

Unfortunately, I still have suppressed blood cells (rbc < normal), so I am not convinced taking something toxic is "good" for me. However, in low dose, maybe it's just fine to take forever. 

 

Can you imagine Dasatinib, off patent, sold over the counter at your local Walgreens for $29.99 as an anti-aging pill? 


Diagnosed 11 May 2011 (100% FiSH, 155% PCR)

with b2a2 BCR-ABL fusion transcript coding for the 210kDa BCR-ABL protein

 

Sprycel: 20 mg per day - taken at lights out with Quercetin and/or Magnesium Taurate

6-8 grams Curcumin C3 complex.

 

2015 PCR: < 0.01% (M.D. Anderson scale)

2016 PCR: < 0.01% (M.D. Anderson scale) 

March        2017 PCR:     0.01% (M.D. Anderson scale)

June          2017 PCR:     "undetected"

September 2017 PCR:     "undetected"


#2 jmoorhou

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Posted 11 February 2017 - 07:11 PM

Wouldn't that be great......at the end of a week of down to 200 mg Gleevec....I was sick with withdrawal, I actually thought my organs were shutting down.
Diagnosed 3/2014 WBC 28 Non detectable within 3 monthsGleevec 400 mg 5/2014 one hour after dinner really improves nausea300 mg 12/15/2016200 mg and 300 mg Gleevec 2/25/2017 (after 3 years on Gleevec) For last four months taking 300 mg per day. Last CMC showed liver enzymes elevated, went to a good Naturopath and he recommended 4 Tumeric, 10,000 mg Vitamen D, and 3 milk thistle (silymarin) daily. Also use One<p>Day Detox Dandeloin tea, and Nettle Tea and a slice of ginger every day...in two months liver tests were below normal.Janis

#3 kat73

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Posted 12 February 2017 - 11:26 AM

This is great, Scuba, now I can live forever . . . miserably! :D 


Dx July 2009 on routine physical.  WBC 94.  Started Gleevec 400 mg Sept 2009.  MMR at 2yrs.  Side effects (malaise, depression/anxiety, fatigue, nausea, periorbital edema) never improved.  Kidney issues developed because of Gleevec.  Switched to Sprycel 70 mg in Aug 2011.  Above side effects disappeared or improved.  Have been MR3.5 - 4.5 ever since.  Two untreated pleural effusions followed by one treated by stopping Sprycel Jan 2017.  After 9 weeks, PCR showed loss of MMR; re-started Sprycel at 50 mg and in 3 months was back to <0.01% IS.  Pleural effusion returned within a couple of months, same as before (moderate, left side only).  Stopped Sprycel 50 mg for 12 weeks; pleural effusion resolved.  At about a monthoff the drug, PCR was 0.03; at 11 weeks it was 2.06 - lost CCyR? Have returned to 50 mg Sprycel for 3 weeks, intending to reduce to 20 mg going forward.


#4 gerry

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Posted 12 February 2017 - 04:44 PM

Perhaps introducing Sprycel and Tasigna into the general population for increased life expectancy might bring the price down.

#5 scuba

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Posted 12 February 2017 - 04:47 PM

No mention of Tasigna, only Sprycel. So you Tasigna, Gleevec, and other TKI users, you're out of luck.


Diagnosed 11 May 2011 (100% FiSH, 155% PCR)

with b2a2 BCR-ABL fusion transcript coding for the 210kDa BCR-ABL protein

 

Sprycel: 20 mg per day - taken at lights out with Quercetin and/or Magnesium Taurate

6-8 grams Curcumin C3 complex.

 

2015 PCR: < 0.01% (M.D. Anderson scale)

2016 PCR: < 0.01% (M.D. Anderson scale) 

March        2017 PCR:     0.01% (M.D. Anderson scale)

June          2017 PCR:     "undetected"

September 2017 PCR:     "undetected"


#6 r06ue1

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Posted 14 February 2017 - 09:03 AM

Take Sprycel, get younger, then have a heart attack and die.   ;)


08/2015 Initial PCR: 66.392%

12/2015 PCR: 1.573%

03/2016 PCR: 0.153%

06/2016 PCR: 0.070%

09/2016 PCR: 0.052%

12/2016 PCR: 0.036%

03/2017 PCR: 0.029%

06/2017 PCR: 0.028%

09/2017 PCR: 0.025%

12/2017 PCR: 0.018%

 

 

Taking Imatinib 400 mg


#7 gerry

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Posted 14 February 2017 - 05:06 PM

Something is going to get us sooner or later. :-)

#8 pammartin

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Posted 15 February 2017 - 08:58 AM

Isn't that the truth!






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