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100 Years of Chronic Myeloid Leukemia Prevalence in France


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#1 survenant

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Posted 26 December 2016 - 02:26 PM

See this article

100 Years of Chronic Myeloid Leukemia Prevalence in France

 

See also Pronostic, life expectancy,  quality of life, ..... in chronic myeloid leukemia

 



#2 survenant

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Posted 07 January 2017 - 08:34 PM

Interesting graphics:

 

Estimated number of CML patients by single age and sex, corresponding legal or projected population (and period specific relative survival hypothesis) in france in 1970 (A), 1980 (B), 2000 ©, 2010 (D), 2020 (E) and 2040 (F).



#3 jmoorhou

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Posted 20 January 2017 - 12:33 PM

Wow the numbers are increasingly a lot.
Diagnosed 3/2014 WBC 28 Non detectable within 3 monthsGleevec 400 mg 5/2014 one hour after dinner really improves nausea300 mg 12/15/2016200 mg and 300 mg Gleevec 2/25/2017 (after 3 years on Gleevec) For last four months taking 300 mg per day. Last CMC showed liver enzymes elevated, went to a good Naturopath and he recommended 4 Tumeric, 10,000 mg Vitamen D, and 3 milk thistle (silymarin) daily. Also use One<p>Day Detox Dandeloin tea, and Nettle Tea and a slice of ginger every day...in two months liver tests were below normal.Janis

#4 xGunner

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Posted 21 January 2017 - 12:53 AM

I don't see anything too surprising. 1980 looked a lot like 1970 because all of the folks from 1970 were dead. 2000 started to increase in numbers, probably due to better success with transplants and the introduction of TKIs. Those folks were alive in 2010, plus joined by new patients. The future projected years show the survivng TKI folks getting older, and eventually dying from other causes.

 

There looks to be some increase in numbers beyond survivability, this could be that tests to detect CML have improved, or that more people are being screened and diagnosed? Or that the surveyed population had also increased.

 

I think it is a positive story in that you can see more people growing old while having the disease. The article shows that the 10 year survival rate was 10% in the late 80s, 80% in 2006, and 84% in 2016. They show it maxing out at 90% in 2060.  With a predicted stable rate of 30 cases per 100,000 people, it will continue to be a somewhat rare disease, but quite survivable.






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