I just got my lab back my AST level jumped from 24 to 39, I've been on Gleevec for 2 1/2 years. The normal level is 36.
Trey can you weight in, has this happened to anyone else?
AST Levels increasing
Started by
jmoorhou
, Dec 13 2016 01:14 PM
3 replies to this topic
#1
jmoorhou
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Posted 13 December 2016 - 01:14 PM
Diagnosed 3/2014 WBC 28 Non detectable within 3 monthsGleevec 400 mg 5/2014 one hour after dinner really improves nausea300 mg 12/15/2016200 mg and 300 mg Gleevec 2/25/2017 (after 3 years on Gleevec) For last four months taking 300 mg per day. Last CMC showed liver enzymes elevated, went to a good Naturopath and he recommended 4 Tumeric, 10,000 mg Vitamen D, and 3 milk thistle (silymarin) daily. Also use One<p>Day Detox Dandeloin tea, and Nettle Tea and a slice of ginger every day...in two months liver tests were below normal.Janis
#2
Rinrin
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Posted 13 December 2016 - 02:52 PM
Hi Janis
I am on Sprycel and also noticed a jump in my AST and my Oncologist thought it might be from Tylenol. I was going through some horrible dental work so had been taking a lot of Tylenol. I stopped/greatly decreased the Tylenol and my AST went back to normal.
Linda
#3
hannibellemo
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Posted 13 December 2016 - 03:33 PM
Hi, Janis,
That's not an increase to be concerned about. Docs don't start getting excited unless the level hits 100. My levels went from 18 to 89 to 500 and finally topped out at 1500. Not a good thing but I had no damage and after stopping Gleevec it was back to within normal range in 7 weeks. I've never had a blip with Sprycel.
Our clinics high normal is 44. Your clinic is very conservative if 36 is their high normal.
Pat
"You can't change the direction of the wind but you can adjust your sails."
DX 12/08; Gleevec 400mg; liver toxicity; Sprycel 100mg.; CCyR 4/10; MMR 8/10; Pleural Effusion 2/12; Sprycel 50mg. Maintaining MMR; 2/15 PCRU; 8/16 drifting in and out of undetected like a wave meeting the shore. Retired 12/23/2016! 18 months of PCRU, most recent at Mayo on 7/25/17 was negative at their new sensitivity reporting of 0.003.<p>
#4
jmoorhou
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Posted 13 December 2016 - 04:19 PM
Pat, thanks so much.
Diagnosed 3/2014 WBC 28 Non detectable within 3 monthsGleevec 400 mg 5/2014 one hour after dinner really improves nausea300 mg 12/15/2016200 mg and 300 mg Gleevec 2/25/2017 (after 3 years on Gleevec) For last four months taking 300 mg per day. Last CMC showed liver enzymes elevated, went to a good Naturopath and he recommended 4 Tumeric, 10,000 mg Vitamen D, and 3 milk thistle (silymarin) daily. Also use One<p>Day Detox Dandeloin tea, and Nettle Tea and a slice of ginger every day...in two months liver tests were below normal.Janis
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