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Millionaire couple who helped fund search for cancer cure honoured at university

Started by r06ue1 , Jun 21 2016 05:56 AM

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#1 r06ue1

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426 posts

LocationEarth, Solar System, Milky Way, Local Group, Virgo Supercluster, Laniakea

Posted 21 June 2016 - 05:56 AM

This is the couple that saved the Glasgow research for curing CML.

http://www.heraldsco...mmentSort=score

I wonder why the funding fell through in the first place?

08/2015 Initial PCR: 66.392%

12/2015 PCR: 1.573%

03/2016 PCR: 0.153%

06/2016 PCR: 0.070%

09/2016 PCR: 0.052%

12/2016 PCR: 0.036%

03/2017 PCR: 0.029%

06/2017 PCR: 0.028%

09/2017 PCR: 0.025%

12/2017 PCR: 0.018%

Taking Imatinib 400 mg

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#2 kat73

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884 posts

LocationWashington, DC area

Posted 21 June 2016 - 11:15 AM

I also wonder what she took for 6 months (hydroxyurea? interferon? or a TKI?) and then why she had a transplant. I also wonder if she's still on gleevec, as she appears to have the pale skin and gleevec eyes. All this is beside the point, sorry.

Dx July 2009 on routine physical. WBC 94. Started Gleevec 400 mg Sept 2009. MMR at 2yrs. Side effects (malaise, depression/anxiety, fatigue, nausea, periorbital edema) never improved. Kidney issues developed because of Gleevec. Switched to Sprycel 70 mg in Aug 2011. Above side effects disappeared or improved. Have been MR3.5 - 4.5 ever since. Two untreated pleural effusions followed by one treated by stopping Sprycel Jan 2017. After 9 weeks, PCR showed loss of MMR; re-started Sprycel at 50 mg and in 3 months was back to <0.01% IS. Pleural effusion returned within a couple of months, same as before (moderate, left side only). Stopped Sprycel 50 mg for 12 weeks; pleural effusion resolved. At about a monthoff the drug, PCR was 0.03; at 11 weeks it was 2.06 - lost CCyR? Have returned to 50 mg Sprycel for 3 weeks, intending to reduce to 20 mg going forward.