Hello Trey and everyone, I was diagnosed March 2014 with CML, treated with Imatinib 300 mg. daily. I had an appointment with the Hematologist today. My PCR BCR/ABL from July 2015 was 0.24%, August 2015 0.22%, September 2015 0.18%, November 2015 0.18%. I asked him when do you increase the Imatinib dosage and he said if it goes up to 1.0% he will prescribe another medication. If I have a choice I would like to increase the Imatinib dosage before I change meds. He said that 400 mg. of Imatinib is for man like me that weighs 230 to 240 lbs. My CBC test result from today was excellent, only the LACTATE DEHYDROGENASE (cell turnover) was 633H Reference range 313-618. Your opinion is appreciated. He ordered another QPCR bcr/abl test today, he will receive the results in 36 to 40 days.
I told him that I really would like to reach 0.1% Major Molecular Response. He said that this lab uses .15% IS as MMR and that I am really close. I said in all the books that I have read 0.1% is Major Molecular Response. I hate when he tells me that .15% is MMR. Thank you.