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Bone Pain?

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#1 RobbinsNest


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Posted 24 June 2015 - 03:36 PM

So I was wondering if anyone has had bone pain as a side effect from taking Tasigna? I've been taking it for around 4 months and haven't had any really bad reactions (except for the damn ITCHING!!!). A couple of days ago, The ends of my Femurs began hurting. It got to the point that I could barely walk. Over the past few days the severity of the pain has lessened but still persists. Has anyone had something like this happen? I haven't felt this type of bone pain since before my diagnosis. Needless to say, I'm a bit concerned. 


Thanks for any help!!!




P.S - I did call my Onc. Just waiting for him to call back.

#2 Frogiegirl


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Posted 24 June 2015 - 04:25 PM

Yep. ...my first few months on tasigna I couldn't walk straight down the stairs. ..I walked sideways because it hurt so bad to bend my legs like I had ran a marathon or something.....I still have aches and pains. But not as intense.

Diagnosed Oct 2013 Started 600mg of Tasigna  on Nov 4th. Lowered dose a few months later to 300mg due to side affects stayed here declining PCR until March 2015 small jump from 0.0072 to 0.0083 scarred my doc into full dose of Tasigna again 600mg(been miserable since) but reached PCRU 06/15/2015(next test) and have been there ever since. Hoping to have another little one. I have the support of my doc to go off anytime, just scared to jump. might go two years PCRU but he said it wont make much of a difference. I just figured I could possibly go into a trial while preggers if I got the two years behind me.

Nov 8th 2017 went off Tasigna

Dec 1st PCRU off TKI

Jan 5th PCR Detected .0625

Feb 1st PCR Detected .7815

Added 8-6 grams Curcumin daily in Feb

March 3rd PCR Detected 3.2646 YIKES!

 stopped trying for baby after February reading. will start new TKI march 16th 2017 (Sprycel)

FYI I'm not done trying for my last little one.

#3 Trey


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Posted 24 June 2015 - 04:42 PM

All TKI drugs can cause accelerated mineral turnover in the bones.  This does not mean they get weaker, just that they turn over minerals more quickly.  This process can cause pain, often in legs bones since they must support the weight of the body.  Because the bones are dense it can take a while for the bone pain to develop.  But it will usually lessen over time as the body adapts.

#4 rcase13


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Posted 24 June 2015 - 06:27 PM

Yep been there on Tasigna. It slowly went away. It was really bad for me. I could not even walk. My wife had to help me to the bathroom.

Now 9 months later I have little to no bone pain. Sadly the itchy head never went away completely.

10/01/2014 100% Diagnosis (WBC 278k, Blasts 6%, Spleen extended 20cm)

01/02/2015 0.06% Tasigna 600mg
04/08/2015 0.01% Tasigna 600mg
07/01/2015 0.01% Tasigna 600mg
10/05/2015 0.02% Tasigna 600mg
01/04/2016 0.01% Tasigna 600mg
04/04/2016 PCRU Tasigna 600mg
07/18/2016 PCRU Tasigna 600mg
10/12/2016 PCRU Tasigna 600mg
01/09/2017 PCRU Tasigna 600mg
04/12/2017 PCRU Tasigna 600mg
10/16/2017 PCRU Tasigna 600mg
01/15/2018 PCRU Tasigna 600mg


Cancer Sucks!

#5 RobbinsNest


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Posted 25 June 2015 - 09:00 AM

Thanks everyone for your feedback. I definitely feel more at ease.

#6 Puneet



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Posted 28 June 2015 - 12:07 AM

My wife has bone pain in her right thigh. She has been taking Sprycel 70 mg. It goes to the point that she has to stop walking or whatever she is doing till the pain goes over.

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