Hi all. I'm hoping for some feedback...
I was diagnosed at the end of January with a BCR-ABL of 195% (WBC 220,000, FISH 20/20), and started on Gleevec 400 mg in early February. Now after 3 months, my BCR-ABL is down to 16% (and WBC down to 3,200). My Onc says he's not terribly worried, but that if I'm not down to .01% at six months (when we do a BMB for PCR, and FISH) he's going to consider switching my drug.
Has anyone else had their PCR results go down this slowly, and what was your eventual outcome? It seems that I keep reading about folks hitting .01 at 3 months. But has anyone's results gone slower but still hit the target?
I'm religious about taking my Gleevec, and haven't missed doses. I have struggled with side effects (muscle/joint pain, nausea, fatigue, very bad rash), but have now come out the other side with all of them. I am nervous about switching, but of course, want a better result.
Thanks so much,