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I really hate to bring this up but I googled heart disease and gleevec and this awful article in the NY Times that lists Gleevec with two other drugs as ones that cause heart disease.


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#1 jmoorhou

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Posted 16 June 2014 - 10:20 PM

Tell me it ain't so.  The good news it's from 2009.  Google "heart disease and Gleevec"  it's the third article.  Yikes!


Diagnosed 3/2014 WBC 28 Non detectable within 3 monthsGleevec 400 mg 5/2014 one hour after dinner really improves nausea300 mg 12/15/2016200 mg and 300 mg Gleevec 2/25/2017 (after 3 years on Gleevec) For last four months taking 300 mg per day. Last CMC showed liver enzymes elevated, went to a good Naturopath and he recommended 4 Tumeric, 10,000 mg Vitamen D, and 3 milk thistle (silymarin) daily. Also use One<p>Day Detox Dandeloin tea, and Nettle Tea and a slice of ginger every day...in two months liver tests were below normal.Janis

#2 Trey

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Posted 18 June 2014 - 11:51 AM

Later research and patient experience does not back up those earlier reports.  If a patient is elderly they may want to keep a closer watch on heart issues, but that is true for any elderly person, Gleevec or not.

Recent data found that there wer only 6 cardiovascular events in 280 Imatinib patients surveyed, and "85% of these patients with cardiovascular events had at least one prior risk factor and were not optimally managed for hyperglycemia and hypercholosterolemia"

http://www.cmladvoca...nd-side-effects



#3 jmoorhou

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Posted 18 June 2014 - 11:03 PM

Thanks for that Trey.  Novartis does say that is why they don't want to give up the patent, because they have made improvements.  And this article was 5 years ago.


Diagnosed 3/2014 WBC 28 Non detectable within 3 monthsGleevec 400 mg 5/2014 one hour after dinner really improves nausea300 mg 12/15/2016200 mg and 300 mg Gleevec 2/25/2017 (after 3 years on Gleevec) For last four months taking 300 mg per day. Last CMC showed liver enzymes elevated, went to a good Naturopath and he recommended 4 Tumeric, 10,000 mg Vitamen D, and 3 milk thistle (silymarin) daily. Also use One<p>Day Detox Dandeloin tea, and Nettle Tea and a slice of ginger every day...in two months liver tests were below normal.Janis




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