In January, when I learned I was no longer in MMR (.083 to .537) I decided to see a second oncologist (the one who originally diagnosed my CML.. His PCR came back 0.220. Though the two were quite a bit different they indicated I was no longer in MMR. I increased my Geevec to 600 mg daily. This week I received my most recent PCR results from both Oncologists. One showed that I had once again achieved MMR with 0.040, but the other lab reported that I had gotten worse (0.220 to 0.390). We are all scratching our chins over this. Both labs are showing all my other values (cbc and white differential) to be normal. We have decided to run pcr's again in 2 months, as long as the other values remain normal. I will continue on Gleevec 600 mg.