Hi sorry to bring this up. When I was taking 400 mg of Gleevec I got an unproductive cough and some shortness of breath......it was solved with a diuretic that has now given me gout.....any ideas anyone?
Pleural Effusion and Gout with Gleevec
Started by
jmoorhou
, Jun 08 2014 01:33 AM
10 replies to this topic
#1
jmoorhou
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Posted 08 June 2014 - 01:33 AM
Diagnosed 3/2014 WBC 28 Non detectable within 3 monthsGleevec 400 mg 5/2014 one hour after dinner really improves nausea300 mg 12/15/2016200 mg and 300 mg Gleevec 2/25/2017 (after 3 years on Gleevec) For last four months taking 300 mg per day. Last CMC showed liver enzymes elevated, went to a good Naturopath and he recommended 4 Tumeric, 10,000 mg Vitamen D, and 3 milk thistle (silymarin) daily. Also use One<p>Day Detox Dandeloin tea, and Nettle Tea and a slice of ginger every day...in two months liver tests were below normal.Janis
#2
MACELPatient
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Posted 09 June 2014 - 01:34 PM
When I first started my Gleevec therapy I was given a prescription for any gout that could arise. Talk with your Dr about that.
#3
GerryL
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#4
jmoorhou
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Posted 09 June 2014 - 06:45 PM
ok thanks Gerry
Diagnosed 3/2014 WBC 28 Non detectable within 3 monthsGleevec 400 mg 5/2014 one hour after dinner really improves nausea300 mg 12/15/2016200 mg and 300 mg Gleevec 2/25/2017 (after 3 years on Gleevec) For last four months taking 300 mg per day. Last CMC showed liver enzymes elevated, went to a good Naturopath and he recommended 4 Tumeric, 10,000 mg Vitamen D, and 3 milk thistle (silymarin) daily. Also use One<p>Day Detox Dandeloin tea, and Nettle Tea and a slice of ginger every day...in two months liver tests were below normal.Janis
#5
hannibellemo
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Posted 10 June 2014 - 09:44 AM
I'm curious, where does the Pleural Effusion come in here?
Pat
Pat
"You can't change the direction of the wind but you can adjust your sails."
DX 12/08; Gleevec 400mg; liver toxicity; Sprycel 100mg.; CCyR 4/10; MMR 8/10; Pleural Effusion 2/12; Sprycel 50mg. Maintaining MMR; 2/15 PCRU; 8/16 drifting in and out of undetected like a wave meeting the shore. Retired 12/23/2016! 18 months of PCRU, most recent at Mayo on 7/25/17 was negative at their new sensitivity reporting of 0.003.<p>
#6
jmoorhou
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Posted 10 June 2014 - 11:14 AM
Oh I'm just complaining, the tests are coming back and no gout so far. But I do feel a tightness in my chest....do you ever feel that?
Diagnosed 3/2014 WBC 28 Non detectable within 3 monthsGleevec 400 mg 5/2014 one hour after dinner really improves nausea300 mg 12/15/2016200 mg and 300 mg Gleevec 2/25/2017 (after 3 years on Gleevec) For last four months taking 300 mg per day. Last CMC showed liver enzymes elevated, went to a good Naturopath and he recommended 4 Tumeric, 10,000 mg Vitamen D, and 3 milk thistle (silymarin) daily. Also use One<p>Day Detox Dandeloin tea, and Nettle Tea and a slice of ginger every day...in two months liver tests were below normal.Janis
#7
td1961
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Posted 10 June 2014 - 03:08 PM
Jmoorhou, You might have a PE or just congestion. The only way to tell is go get a chest x-ray. Then, you may be told to get a CT Scan of the chest and maybe an Echo of the heart. This would be to check for PAH. I have had both and still use 2.5L of oxygen at night. Sprycel is usually the culprit but other TKI's also can cause it. Don't guess because PAH is nothing to play with. Once you have it, you will live with it so best not to get it in the first place. Good Luck! TracyD
#8
ThePlum
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Posted 16 June 2014 - 09:21 AM
Jmoorhou, I am on Sprycel & have had just about every side effect listed. I had pleural effusion & also pericardium effusion. I ended up in the hospital for 3 weeks & had to have painful surgery to remove fluid & blood clots. By all means, always get a chest xray for any persistent cough!
#9
jmoorhou
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Posted 16 June 2014 - 09:27 PM
Do you know the name of the gout medication? Thanks so much.
Diagnosed 3/2014 WBC 28 Non detectable within 3 monthsGleevec 400 mg 5/2014 one hour after dinner really improves nausea300 mg 12/15/2016200 mg and 300 mg Gleevec 2/25/2017 (after 3 years on Gleevec) For last four months taking 300 mg per day. Last CMC showed liver enzymes elevated, went to a good Naturopath and he recommended 4 Tumeric, 10,000 mg Vitamen D, and 3 milk thistle (silymarin) daily. Also use One<p>Day Detox Dandeloin tea, and Nettle Tea and a slice of ginger every day...in two months liver tests were below normal.Janis
#10
hannibellemo
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Posted 17 June 2014 - 05:42 AM
Allopurinol.
Pat
Pat
"You can't change the direction of the wind but you can adjust your sails."
DX 12/08; Gleevec 400mg; liver toxicity; Sprycel 100mg.; CCyR 4/10; MMR 8/10; Pleural Effusion 2/12; Sprycel 50mg. Maintaining MMR; 2/15 PCRU; 8/16 drifting in and out of undetected like a wave meeting the shore. Retired 12/23/2016! 18 months of PCRU, most recent at Mayo on 7/25/17 was negative at their new sensitivity reporting of 0.003.<p>
#11
pammartin
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Posted 30 July 2014 - 11:09 PM
PAH is nothing to mess with and unfortunately I speak from first hand experience. Don't let it go without testing and doctors. I was in ER three times with BP hovering in mid 70's/40's. They would send me home with chest pain. After weeks of shortness of breath I went by ambulance to hospital. Next day I was in ICU then heart cath and off to second hospital and finally transferred to Pittsburgh at PH specialty cardiologist. Please pay attention. Going in for check and being told you are ok is positive, but you know yourself better than anyone. Had I pushed harder, perhaps I would not have this CADD pump attached to me constantly providing drug for PH. Take care!!
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