ASH 2013 begins 7 December. Abstracts are available online and show some interesting developments.
There are several papers linking Vitamin D levels and synergistic response with TKI's to limit CML progenitor and stem cells.
One paper, in particular, is noteworthy:
As it turns out, I learned last July during my first Physical in some 15 years that I was very low in vitamin D ! (D < 17) (http://www.lef.org/m...d-Levels_01.htm)
And probably have been for years - certainly leading up to CML diagnosis. I began taking 10,000 I.U. vitamin D3 as prescribed by my primary physician (which becomes Vitamin D in the body) to increase my blood level.
Over three months I was able to increase my vitamin D level from 17 to 29 ng/ml and recently it is now 49 ng/ml (once I started to take it with food that has fat). My goal is to get my level to around 60. I am now on a maintenance dose of 5,000 I.U. per day.
Adults are recommended to take at least 5,000 I.U. per day of Vitamin D3. But having it measured twice per year is necessary to know for sure if you are taking the correct amount.
As some here know, I have been trying to get to PCRU - hovering just above it for over a year. I take low dose Sprycel in combination with Curcumin which has given me satisfactory results. However, when I started to increase my vitamin D level, three months later my PCR level was cut in half. I go for my next test in a week or so and maybe this time I will be PCRU.