I have not been on the boaard for a while (not even sure how long it has been) out of frustration but today I was looking for some info and know this is the best place to find it Thank you all for being a wonderful font of knowledge. I was DX in March 2010 and started G400 right away. I hit FISH neg after a few months but the PCR numbers were very slow moving. I had asked my Onc several times about a drug switch and he kept saying he was not in favor of that. In March 2013 I finally hit MMR and started to feel encouraged once again that maybe I would see PCRU soon. When I had my bloodwork done in June I saw a 1.3 log increase in my PCR from the March number. I had to switch docs between March and June because the first one retired. The new Onc said it was possible it was a fluke and to wait a few months and repeat the bloodwork. I had the bloodwork done a few weeks ago and the PCR number was even higher. I had a BMB a week and a half ago to check for mutations. I saw the doc today and there are no mutations so I am going to switch to Sprycel. I am seriously hoping for a better side effect profile and a much better response.
So, who can give me some encouragment that when they made the switch they felt so much better?