Advanced Member
Posted 27 September 2013 - 07:49 AM
International Scale:
BCR-ABL1/ABL1 BCR-ABL/GUS
04.11.12 76% 21%
06.14.12 17% 10%
07.26.12 3% 3%
10.24.12 0.10% 0.08%
01.15.13 0.02% 0.01%
04.11.13 0.03% 0.01%
07.16.13 0.04% 0.03%
09.12.13 0.01% 0,02%
Needless to say, i am one happy camper today
Thank you Gleevec!!!!
Hope everyone is doing good.
Teddy
Member
Posted 27 September 2013 - 08:11 AM
Congratulations, Teddy! Happy for you!!
DX 09-2011 PCR 8.08 not IS WBC 17 , Began Tasigna 600mg
in 2012 Tasigna 450mg/day ,in 2013-2017 Tasigna 300mg/day
DATE/PCR
09-11/ 8.08 not IS
03-12/ 0.054 not IS
06-12/ 0.035 not IS
09-12/ PCRU, 01-13/ PCRU
4-13/ 0.042 IS
7-13/ 0.014 IS
11-13/ PCRU, 04-14/ PCRU
8-14/ 0.006 IS
PCRU: 12-14/ 05-15/ 10-15/ 02-16/
09-16/ 02-17/ 09-17/
10-17 tapered off
11-3-17 Stopped Tasigna
1-15-18 still PCRU
Advanced Member
Posted 28 September 2013 - 09:39 AM
Way to go, Teddy!
Pat
Pat
"You can't change the direction of the wind but you can adjust your sails."
DX 12/08; Gleevec 400mg; liver toxicity; Sprycel 100mg.; CCyR 4/10; MMR 8/10; Pleural Effusion 2/12; Sprycel 50mg. Maintaining MMR; 2/15 PCRU; 8/16 drifting in and out of undetected like a wave meeting the shore. Retired 12/23/2016! 18 months of PCRU, most recent at Mayo on 7/25/17 was negative at their new sensitivity reporting of 0.003.<p>
Advanced Member
Posted 28 September 2013 - 01:11 PM
It is interesting seeing the differences between control genes (ABL1 vs GUS). Your stats also help point out an issue that at the higher levels the PCR is fairly variable in reliability. Then at the lower levels it is more consistent even with different control genes.
Another thing to point out is that your "personal PCR" is a 3 log reduction from diagnosis using GUS and just over 3 log using ABL1; but by International Standard (IS) you have a 4 log reduction given that the standardized 3 log reduction is .1% Either way you are doing very well. Just interesting to look at the data.
Advanced Member
Posted 29 September 2013 - 03:58 PM
Thanks for the support guys/girls
New Member
Posted 29 September 2013 - 08:38 PM
Teddy,
Great response, Congratulation.
Advanced Member
Posted 29 September 2013 - 08:46 PM
Congratulations Teddy!!! Celebrate your wonderful news!!!
Susan
Advanced Member
Posted 30 September 2013 - 04:12 PM
Thank you!
Hope all is well with you Ray.
Yes, Susan, i had a few glasses of red wine last night to celebrate
Starting to relax a bit more now, hope the good response continues so i can get on with my life and stop worrying so much.
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