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#1 eithne01


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Posted 27 June 2012 - 03:23 AM

Hi everyone, Has anybody here on a TKI being diagnosed with hardening of the leg arteries after being on treatment for two years? symptoms starting

shortly after beginning treatment?

#2 TeddyB


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Posted 27 June 2012 - 03:49 AM

Which TKI are you on? Sprycel?

It can cause pulmonary arterial hypertension, but i have never heard of hardening of the leg arteries due to a tki, even though i am fairly new to CML. Im sure some of the other board residents can help you out.

#3 Trey


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Posted 27 June 2012 - 12:47 PM

Peripheral arterial occlusive disease (PAOD) has been associated with Tasigna in some rare cases where other diseases (such as diabetes, etc) were also present. 



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