Your BMB result 46, XY t(9,22) (Q34, Q11.2) 46 XY (13) means:
- The 46 XY bit means you are a human male (okay, possibly a ground squireel, or one of a few other animals with 46 chromosomes)
- The t(9,22) etc means that you have the CML translocation
- The important bit is the 46 XY (13) at the end which means that 13 out of the 20 cells were normal ie CML free.
That works out as 35% CML positive which is bang on a partial cytogenetic response? which is the target for 6 months so you just squeak into the 'optimal response' band.
From your position you could arguie for any option out of stay on 400, switch to another drug or increase to 600. I would only go the last of those routes is you have been pretty well side-effect-free on 400. If you want a faster response then a more powerful drug (if Sprycel of Tasigna is available to you) would generally be a better bet than increasing the dose of Gleevec, but that's only my personal opinion. If you are absolutely fine on 400 G then one can see the attraction of increasing to 600 to see if you get a faster response as 'the devil you know'.