4 replies to this topic

[Taylor]

Hi all,

I'm thinking about changing my dosing schedule with Tasigna (150mg x 2 bid).  I have been doing 10:30AM in the morning and 9:30-10PM at night.  I want to do something like 6AM and 5PM.  With work and just my schedule now that I'm married, I end up getting up around 6AM anyway but I don't eat until after 7.  Also the 5PM will help a lot with eating and drinking later for social reasons.

I am wondering if I need to do anything special fror making a change like this.  I know Tasigna can be, if necessary, dosed on a 16/8 hour interval, but I'm kind of worried about doing a 12 hour interval after the 8 hour after making this switch (i.e., taking it at 10AM, then 6PM, then again at 6PM).  It would probably just work out of my system in a day, but I wanted to be sure I shouldn't try to skip a dose and "reset" or anything like that.  Thanks,

Taylor

[Lori's okay]

HI Taylor,

Not completely sure I understand your concern.

But, if you take it at 9:30 or 10 at night then at 6am the next morning that would be 8 1/2 to 8 hours.  That should not be a problem.  My only worry would be if you needed to take it less than 8 hours apart.  I'd worry more about going a little too high on the blood levels than too low.  Anyway you cut it, we all miss a dose now and then and the world does not end.  I try to nearly never miss, and think that's important.  But, my onc is much more comfortable with a miss now and then. 

(I am on 450mg a day, taken one in am and two in pm....so obviously my blood levels vary, I'm early in treatment but responding really well.)

Good luck.

Lori

[Melanie]

Hi Taylor,

I take my doses at about 6:00 am and 4:30-5:00 pm. Works fine. Sometimes due to afternoon activities, (eating late lunches, snacking with the grandchildren, etc) I don't get the 5 pm one on time and have to move it to later after dinner. End up delaying it to 9 - 10 pm. I haven't noticed any big difference.  Hope that helps.

Blessings, Melanie

[sarabrooks83]

I think once you make the switch and commit to it, you'll be fine! The body responds very well to routine, so just make sure that the first week on your new schedule is solidly in place. Maybe try setting an alarm on your phone in order to remind yourself during the initial switch over period!