21 replies to this topic

[akjones]

Your BCR/ABL tests look almost exactly like mine. My opinion is that the test is only accurate +/-0.5 log. You look to be a 2.5 log responder just like me... Good but not great. I've tried all three TKIs G, T and S. Same result each time. I have no mutations. But if you read the literature the risk of the disease advancing if you hover between 2.0 and 3.0 really is only very slightly higher than if you are solidly below 3.0. I have settled on S for now as the side effects are the mildest. May switch to P or B in a year or two, in no rush until there is more history.

Andy

[Trey]

CB,

You are statisically stable, but short of MMR.  I would not worry about side effects so much and try to treat the disease and get below MMR.  The kinase mutation test is not very useful below CCyR, and mutations cause more rapid jumps than you have experienced.  Sprycel would be a reasonable alternative at this point.