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New approach to treating CLL (somewhat related to CML in terms of approach to treatment)


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#1 HPL

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Posted 10 August 2011 - 10:54 PM

What is most remarkable, is the approach, using the body's own immune system to fight. I know there has been a few discussions here, this seems to be one of the first reports coming out that patients have been put in remission from the treatment. It's amazing what new and exciting things are on the horizon...

http://www.msnbc.msn...t-expectations/ 



#2 scuba

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Posted 11 August 2011 - 12:31 PM

Imagine that this approach really works.   One goes in for a DNA type of analysis and the doctors create unique T-cell response custom to you and a month later, the CML is dramatically reduced - maybe even eradicated by ones own immune system.  You take your TKI bottle and throw it away - all $5,000 worth.

So ... what happens to Gleevec, Sprycel, Tasigna ....etc. etc.  Doesn't anyone care about the lost profits of big-Pharma?  What about them?  It's not fair I tell you.  They worked hard to help us (and make billions - but whose counting) - and to suddenly make their drugs obsolete - even useless ...

In the board room of Bristol Meyers Squibb, a business man reports that competitors at the Univ. of Penn - have found a way to elimininate the TKI market. I wonder what they will do.

Here is info on the Doctor and his research interests.  It's all about T-cells:

http://www.med.upenn....php/g275/p2328


Diagnosed 11 May 2011 (100% FiSH, 155% PCR)

with b2a2 BCR-ABL fusion transcript coding for the 210kDa BCR-ABL protein

 

Sprycel: 20 mg per day - taken at lights out with Quercetin and/or Magnesium Taurate

6-8 grams Curcumin C3 complex.

 

2015 PCR: < 0.01% (M.D. Anderson scale)

2016 PCR: < 0.01% (M.D. Anderson scale) 

March        2017 PCR:     0.01% (M.D. Anderson scale)

June          2017 PCR:     "undetected"

September 2017 PCR:     "undetected"


#3 scuba

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Posted 11 August 2011 - 02:04 PM

More info:

http://www.newsmaxhe...omo_code=CD13-1


Diagnosed 11 May 2011 (100% FiSH, 155% PCR)

with b2a2 BCR-ABL fusion transcript coding for the 210kDa BCR-ABL protein

 

Sprycel: 20 mg per day - taken at lights out with Quercetin and/or Magnesium Taurate

6-8 grams Curcumin C3 complex.

 

2015 PCR: < 0.01% (M.D. Anderson scale)

2016 PCR: < 0.01% (M.D. Anderson scale) 

March        2017 PCR:     0.01% (M.D. Anderson scale)

June          2017 PCR:     "undetected"

September 2017 PCR:     "undetected"





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