I had funtional endoscopic sinus surgery last November at the Mayo Clinic in Rochester, MN. It was done under general anesthesia and my platelet count at the time was probably around 160-180 ("normal" for me). I asked him how high platelets had to be for him to do surgery and he said he had had to do surgery on people with very low counts, 20-25, with excellent results. He said how well the platelets function is just as, if not more so, important. He knew I was taking Sprycel and he knew about the possible platelet function issues.
I had been on Spycel for a little over a year when I had my surgery. There is no doubt my platelet function is not perfect - I have occasional bouts of petechiae, purpura, but not much bruising (go figure). I seem to find plentyof occasions to tear my skin in some fashion and I don't seem to have clotting issues. BTW, I took my Sprycel as soon as I felt like eating after surgery so I never missed a day. I had no excessive bleeding during or after the surgery.
Another important thing to know is the expected "normal" blood loss for the kind of surgery you are discussing because that can vary. My husband will be having endoscopic robotic surgery for prostate CA in the near future vs the more common radical retro pubic procedure. The difference in blood loss can be as much as the expected 3 oz. blood loss in the robotic to as much as two units in the retro pubic. I mention this because I was very surprised there could be such a wide range.
If you haven't yet, I would make my surgeon aware of the possible platelet function issue wth Sprycel so he/she can take that into consideration. (Just call me Ms. Obvious.)