Hi Everyone !
My mother has been on Gleevac for 8 months now and has only reached a close to 1 log reduction. Her report says BCR-ABL translocation out of range is 12.35%
Our Onc increased her dosage from 400 mg to 500 mg 3 months back. He wants us to wait till she completes 12 months and then decide if a switch in the medicine is necessary or not.
This is keeping me very worried .. Any thoughts or past experiences are most welcome around the time it takes for complete cytogenetic remission.
Also to add to this, she has been going to through a severe facial water retention especially around her eyes and cheeks for the last 2 days. Today it was worse and she was having difficulty even opening her eyes.
Talked to the doc and he has asked to run a couple of tests like Kidney function test and Liver function test etc.Results are awaited.
I wanted to know if someone has experienced severe facial edema and what was the line of treatment, I searched the net for causes and got even more concerned when I read about kidney diseases and functioning problems.
Can 500 mg of Imatinib cause kidney problems leading to extreme facial edema or is this just a side effect.
She has experienced swelling around her eyes before and it usually goes away with a mild dosage of lasik.But this time it seems pretty bad.
Trey, hoping for some answers from you and other.