2 replies to this topic

[cpsn0000]

After 6 months of not being able to stay on any medications due to severe platelet reductions, I am being prepared to have to go through the stem cell transplant process. I was only able to stay on Sprycel for 2 weeks at 20mg before my platelets fell below 10,000. I am in CHR w/no evidence of cml but my FISH came back still at 100% ph positive.

I am considering working with Dr. Cortes or Dr. Talpaz to see if there are any other clinical trials I can become part of but don't qualify for Ponatinib because of having a severe rash on Tasigna.Doing the stem cell transplant now gives me the best chances of doing well but the GVHD is the biggest concern. Either way, if we don't treat this somehow, the battle will be lost anyway you look at it.

Any thoughts on this and recommend good transplant hospital. As of now, I will go through Moffitt in tampa for my transplant.

Thanks

[PhilB]

No useful thoughts, but lots of good wishes to you.  Do you have any sibling matches and if not have they checked the registers yet for unrelated donors?  The quality of the match they find might well be an influencing factor on whether to keep looking for clinical trials or head to transplant.

The transplant forum on here has many great people who will be able to give you good advice and support if that is your route.

All the best

Phil

[Trey]

Here is the info on Moffit as a transplant center.  It is a National Marrow Donor Program (NMDP) approved transplant center, which is a basic necessity for choosing a transplant center.

http://www.marrow.or...534&p_src=state

Here is the info on all NMDP approved centers:

http://www.marrow.or...c_list_by_state

Moffit's statistics are roughly in line with the national average (survival, etc) according to the NMDP.

There is something to be said for the logistics of using a transplant center near your home.  The process will be a logistical issue for family and friends.  But local is not always best.  The most "famous" transplant centers are the Fred Hutchinson Center (Seattle) and MD Anderson (Houston).

I assume you saw my posting on transplant basics:

http://community.lls.../message/101600