So here is my story on Gleevec for 6 years. Just came down with a case of Shingles. Could Gleevec have caused the Shingles? I did splurge on grapefruit juice over Mother's Day and did not know if I increased my Gleevec levels....... Also I am only 43 but have had constant skin issues with Gleevec since I have started it... Any info would help thanks
Shingles
#1
Posted 10 May 2011 - 02:18 PM
#2
Posted 10 May 2011 - 02:42 PM
If it is trully Shingles, then Gleevec likely did not cause it. Shingles is caused by a virus, or actually a reactivation of a virus you had as a kid. Just being run down in general may contribute to it, but I don't see how TKI drug would induce it.
Skin issues appear to be related to the way Gleevec target some other proteins in addition to BCR-ABL. A dermatologist may be able to provide some topical creams that can help.
Just my thoughts, perhaps some others will have comments as well.
#3
Posted 10 May 2011 - 03:58 PM
My dh, not a CMLer, got shingles a few years back. He had been under a good bit of stress and was feeling rundown anyway. Doc figured it was more those factors that allowed it to re-emerge.
Hope it gets better! I think my dh still has some scars from his bout with it.
Traci
#4
Posted 10 May 2011 - 04:02 PM
Hi!
if you check my "Whooppeee" thread of a week or two ago, you will find a very interesting discussion on shingles which I am finally almost over myself. Shingles is actually the reactivation of the Chicken Pox virus which "hides" in the nerves for years until it comes out of hiding (exactly why is still unknown but usually occurs when your immune system is weakened). Check the thread out. There are some good points and/or questions raised.
Vicki
just bumped it up to the top for you :-)
Dxd 2007
started on Gleevec switched to Sprycel 100mg in 2009
PCRU since 2011
20mg Sprycel every other day since Dec. 2014
Began TFR 4-18-16
#5
Posted 10 May 2011 - 08:58 PM
Some of the drug interaction sites mention Shingles as a side effect with Gleevec, though it is rated as "uncommon".
#6
Posted 11 May 2011 - 08:11 AM
morning Jerry,
could you plz give links? Never heard that before and I am not on Gleevec but Sprycel.
Thanks, Vicki
Dxd 2007
started on Gleevec switched to Sprycel 100mg in 2009
PCRU since 2011
20mg Sprycel every other day since Dec. 2014
Began TFR 4-18-16
#7
Posted 11 May 2011 - 07:58 PM
http://doublecheckmd...=41395&eid=1438
There is also a powerpoint slide pack created for The Life Raft Group "Managing Gleevec Side Effects" from Februay 8, 2006 which mentions Shingles - you'll need to Google it as I am unable to provide a link to it.
#8
Posted 12 May 2011 - 07:42 AM
THANK YOU!!!
Dxd 2007
started on Gleevec switched to Sprycel 100mg in 2009
PCRU since 2011
20mg Sprycel every other day since Dec. 2014
Began TFR 4-18-16
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