I have been running a low grade fever for months anywhere from99.2-100 most of the day and night then at other times my temp gets as low a 96.4.I was just wondering if Ishould be concerned b/c my doctors aren't and has anyone else had unrelat bone marrow transplant I am having one in june? Amy
running a constant low grade fever
Posted 09 May 2011 - 09:19 PM
Umbilical cord blood transplantation from unrelated donors in adult patients with chronic myeloid leukaemia.
Presently the frist line therapy is using drugs unless there is a good reason to do HSCT with MUD. There are lots of reasons, of GVD, Wondering if you have any issue on present medication. For HSCT transplant a perfect match of antigen is a requirement 10/10. Unless the disease is out of control and risk is properly considered.
Are you doing Umblicord transplant or HSCT ?
There was a case below that was successfull with UCB transplant as below case, but this case is rare.
Stephen R. Sprague was treated for CML in a 1997 clinical trial--one of the first of its kind for adult patients--using cord blood that was expanded ex vivo.
2006, New York Blood Center's National Cord Blood Program (NCBP)
Posted 09 May 2011 - 09:53 PM
@Trey I didpost on the old message boards,wbc were just a little high can't remember # but my bcr/abl went from 100 copies per 100,000 to 700 copies per 100,00 in about 3 months time.The reason for the transplant is gleevec failed,tasigna failed,and now sprycel is not working as well and causing major side effects.I am having allogeneic bmt with unrelated donor at UNC chapel hill nc
Posted 10 May 2011 - 08:44 AM
Did you have a Kinase Mutation Test done to see if a kinase mutation is causing the poor response? If you have not explored other drugs in clinical trial, a number of folks here are in the Ponatinib trial who would have otherwise needed a transplant:
Do you have a good match for transplant? Hope all goes well..
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