Here is my weekly report. I have been drug free for over 4 months.
Weekly CBC - (week 14 no TKI):
ANC = 0.88 (last week = 0.96)
WBC = 2.5 (last week = 2.6)
RBC = 3.67
HGB = 12.7
HCT = 38.1
MCV = 104
MCH = 34.5
PLT = 221
I had a bone marrow done last week (no results yet) so Dr. Cortes can learn what is going on in my marrow. I expected that my Neutrophils would finally cross over 1.0 so I can re-start Sprycel, but I have to tell you, I am kind of glad that I get another reprieve. I get so close to '1', but it doesn't go over that magic number. My body really seems to be in some sort of steady state. Without any TKI, I thought my counts would just start to rise. Assuming the CML is in a quiescent state, I don't understand why my normal system isn't making up the deficiency. I have been chronically low by half the Neutrophils. And my red blood is somewhat anemic also, but that has been true for almost a year following Gleevec cessation.
This is one strange adventure. To be "sick", but not. To have a disease for which I am not getting treatment and have felt great for over 4 months with no sign of the disease.
And the only thing I can think of is that I take Curcumin. Dr. Bharat B. Aggarwal (M.D. Anderson PhD. not M.D.) does research with Curcumin and he suggested that I increase my dose from 500 mg. per day to 8 grams per day gradually. He is really curious about my case. As long as I am not taking any TKI, the Curcumin is not a problem.
I haven't decided to increase it yet pending my bone marrow. But if my bone marrow shows that the CML has decreased further - then I am going to go the Curcumin route at full 8 grams for 3 months and watch what happens. Imagine if this works.
I was tempted to follow Trey's thoughts on stopping the Curcumin to see if my counts rise - but I don't want to stop a 'maybe' good thing. I love being TKI free. By the way - do blast cells show up in the WBC count? or are they only discovered under the microscope?
I will say this - for those who are PCRU - maybe adding Curcumin to your diet can be a bit of insurance. Just a thought. It's a strong anti-oxidant and anti-inflamatory and when mixed in Curry - tastes good too. 500mg is nothing and I am doing fine. I wonder what 8 grams would do. Probably affect the Sharts.