My other half, Bill, has CML and after about 15 months on Gleevec (9 mo), Sprycel (3 mo), and Tasigna (<3mo), it was discovered that he has the T315i mutation. He is currently in the Ariad/ponatinib drug trial and seems to be responding. He's just over 1 month in.
It seems to me that I read once that about 40,000 new CML cases are diagnosed per year. I may have dreamed that number. But if anyone can tell me the approximate # AND if there's a stat for how many of them have the T315i mutation, I'd like to know. Our hematologist/oncologist has about 40 CML patients, but only 1 that's been dx'd with T315i. I don't think that's enough of a study group to determine that 1 in 40 CML patients has it. :-)
Would be interested in talking to others who have this mutation as well....please respond here if you want to talk, even if you don't know the answer to the question.