My other half, Bill, has CML and after about 15 months on Gleevec (9 mo), Sprycel (3 mo), and Tasigna (<3mo), it was discovered that he has the T315i mutation. He is currently in the Ariad/ponatinib drug trial and seems to be responding. He's just over 1 month in.
It seems to me that I read once that about 40,000 new CML cases are diagnosed per year. I may have dreamed that number. But if anyone can tell me the approximate # AND if there's a stat for how many of them have the T315i mutation, I'd like to know. Our hematologist/oncologist has about 40 CML patients, but only 1 that's been dx'd with T315i. I don't think that's enough of a study group to determine that 1 in 40 CML patients has it. :-)
Would be interested in talking to others who have this mutation as well....please respond here if you want to talk, even if you don't know the answer to the question.
Thank you!
BethS