This just keeps getting interestinger and interestinger.
Just when I thought I was going to re-start on Sprycel - this happens:
ANC = 0.79 (last week = 0.91)
My ANC has dropped on its own without any TKI. I don't understand why it would do this? Supposedly I have CML, my leukemic cells should be growing and increasing in number without anything to stop them (unless my body has figured it out without drugs). I was slowly recovering along the lines of a stem cell transplant patient from January through last week and then this ... FISH is zero but I have a PCR of 35% - admittedly down from January, but it is still 35% transcripts.
What the heck is my bone marrow doing?
I do take curcumin every day (500 mg) - have been since January.
The only thing I can think of is that I hit the running trail this week for the first time in over a year. (I have to get back in shape). Today is day 3. Maybe that is reflected in the sudden drop in ANC? But I thought that mild exercise (just ramping up) caused Neutrophils to go UP, not down.
Bummer - Not that I was looking forward to resuming Sprycel. I believe they may want to do a BMB again. No *#($&# way. And sure enough, my mouth is drier; low neutrophils = dry mouth.