I had a strange thing happen yesterday (have had it once before in my knee). I was getting out of the car, wasn't even touching anything and felt a pain in my thumb. Within 5 minutes it was swollen and purple! The last time it happened my platelets were a little low so the doc on call advised that I go to the ER to get labs and monitor for a blood clot. All turned out negative then. My platelets now are within normal range. Just wondering if anyone else have had this kind of experience? Is Gleevec or CML related or totally random? Although a bit better my thumb is still swollen and purple. I did speak with my onc. today. He indicated he hadn't heard of this kind of event while on Gleevec. He does want to see me tomorrow.