So it was my 3 month mark last month and I sent an email to the physician about a week after getting blood drawn. I asked if i'm getting a PCR and she said that she went to get this tested on my blood at that time. I asked by email what were the results and she said, "congratulations!, you've reached MMR".
So I get all excited and start posting about what is the fastest CMR ever..etc.. I just went this month and this time I asked for a hard-copy of the PCR. When I go home to look at it, it says this:
Current specimen: 2.73 x 10 - 3 (0.273%)
First positive specimen (MP10-1195, October 2010) : 4.02 x 10 - 2
Log decrease relative to the first positive specimen: 1.17
I said, WHAT! This is not MMR, I thought MMR was a 3 log reduction, not a 1.17 reducition. I emailed her telling her that I thought an MMR was a 3 log reduction. She emailed back "Yes you are correct about 3 log reduction, but you started off fairly low tumor burden. Most people may have a 10 to +1 and you had a -1. We call MMR anything below 10 - 3" (10 - 3 ; same as 10 ^ -3; same as 10 to the negative 3).
Just when I thought I was understanding it, I see this and it confuses me more. I don't even know what tumor burden is. My mindset from reading everywhere is that you have to have a 3 log reduction in order to reach MMR.
I just emailed her back and asked if I'm progressing as I should be and she said, absolutely. I'm hoping she's just not trying to make me feel better.
Can any body shed some light if this is truly MMR, also on what is tumor burden, and also how this tumor burden could be -1 if my WBC at that time was around 200,000. Thanks.