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#21 scuba

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Posted 27 January 2018 - 02:21 AM

My whole family's been sick with the flu for three weeks and I haven't got it (touch wood). Haven't had a flu shot for the past one and a half years. Maybe it's the 50mg per day of Sprycel :)

 

Only kidding... it's probably immunity from previous ten years flu shots... but I love the idea of getting a positive side effect (as well as life itself) from Sprycel.

 

https://www.scienced...35964461730017X

 

... seems Sprycel might help you live longer (and not just by keeping CML at bay).


Diagnosed 11 May 2011 (100% FiSH, 155% PCR)

with b2a2 BCR-ABL fusion transcript coding for the 210kDa BCR-ABL protein

 

Sprycel: 20 mg per day - taken at lights out with Quercetin and/or Magnesium Taurate

6-8 grams Curcumin C3 complex.

 

2015 PCR: < 0.01% (M.D. Anderson scale)

2016 PCR: < 0.01% (M.D. Anderson scale) 

March        2017 PCR:     0.01% (M.D. Anderson scale)

June          2017 PCR:     "undetected"

September 2017 PCR:     "undetected"


#22 scuba

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Posted 27 January 2018 - 11:36 AM

https://www.bloomber...s-getting-worse

 

Flu this year is very bad. I can't help but feel much of this could have been avoided or severity lessened if people had their vitamin D level tested and supplemented if their levels were below 50 ng/ml. The sweet spot for full immune protection is between 50-70 ng/ml NOT 20-50 as reported by the medical establishment - although there is debate now on what an ideal blood range should be and some feel 60 is better:

 

https://www.health.h...l-2016121910893

 

Vitamin D is more than a vitamin. It is actually a hormone as many of the body's cell types have vitamin D receptors (making it a hormone in behavior). Cells that are particularly receptive (and activated) by vitamin D are T-cells - specifically the ones which attack virus'. In fact, vitamin D is essential for our immune system to work.

 

https://www.scienced...00307215534.htm

 

When a flu virus particle(s) enter your system, T-cells which have Vitamin D are activated and begin to attack the virus. The more vitamin D available to activate T-cells the faster the response to the flu invader. Low vitamin D levels impede the ability of T-cells to activate. Without vitamin D bound to vitamin D recepter on a T-cell, that T-cell stays inactive. It's like having a stable of attack dogs locked in their kennel while invaders are rampaging the property. Not much good protecting you when they are locked up (full disclosure: we have several Dobermans). Vitamin D "unlocks" the T-cell kennel and lets them out.

 

Why is  flu common in winter? Less sun. Vitamin D is produced by the skin when exposed to strong sunlight. Flu spreads like crazy in winter. In summer - more sun, more vitamin D produced and not enough people to vector the flu virus. Flu is around all year - but only reaches epidemic proportions when enough people have too low a vitamin D level in winter (< ---- my opinion) so the virus can spread like wildfire - as it is doing now. An important note - vitamin D takes time to build up in the body and time to decrease naturally. It is fat soluble and is stored. Half life of vitamin D is two months. This is why flu's peak in winter (as opposed to fall) <---my opinion, once the sun gets weaker, our vitamin D levels start to fall to half - two months later.

 

Its saddens me to think how many people especially young people have died from this years flu who probably also had very low vitamin D levels (because they live in front of computers) and might have been spared.

 

https://news.harvard...t-cold-and-flu/

 

(I use to get the flu all of the time - whenever there was a warning about flu season - sure enough I get it. Almost always in late December in time for Christmas. Little did I know for all these years my vitamin D status was near or below 20 ng/ml. I don't drink milk (which is fortified with some vitamin D (but not enough)) or dairy in general and I avoided the sun because I was told the sun is bad for you (what nonsense now when I look back on that). Getting CML awakened me to nutrition and health overall. With a lot of reading, I learned that vitamin D is vital to our immune system. I increased my vitamin D level to where it is now by supplementing - and I have never had a flu since... or a cold, sneeze or cough either). I just don't get sick anymore even though I am surrounded lately by people sick with the flu - some with severe cases. Those who had their vitamin D level checked, were around 20 - imagine that.)


Diagnosed 11 May 2011 (100% FiSH, 155% PCR)

with b2a2 BCR-ABL fusion transcript coding for the 210kDa BCR-ABL protein

 

Sprycel: 20 mg per day - taken at lights out with Quercetin and/or Magnesium Taurate

6-8 grams Curcumin C3 complex.

 

2015 PCR: < 0.01% (M.D. Anderson scale)

2016 PCR: < 0.01% (M.D. Anderson scale) 

March        2017 PCR:     0.01% (M.D. Anderson scale)

June          2017 PCR:     "undetected"

September 2017 PCR:     "undetected"


#23 thatguy

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Posted 27 January 2018 - 11:44 AM

and did you get the flu?

(in spec ~ 60 ng/ml)

Pretty sure I did. My last test was about a month and a half before though, and my value was 37. Under 20 is listed as deficiency at Quest.
3/25/2015- Dx'ed by FISH : 85% of cells dual-fusion signals, 7% with tri-fusion signals, WBC 212,000. Started Gleevec 400mg.... Calculated .93 SOKAL

08/17/2015- 14.793 % I.S P210 (quest)
10/15/2015- 3.313 % I.S (quest)
12/23/2015- 1.891 % I.S (quest)
1/07/2016- Tasigna 300mg 2x daily
1/14/2016- 4.414 % I.S P210- City Of Hope lab, mutation negative.
1/26/2016- 1.589 % I.S (quest)
2/22/2016- 1.719 % I.S (quest)
2/29/2016- 1.133 % I.S (quest)
3/03/2016- Tasigna 400mg 2x daily.
3/29/2016- 0.663 % I.S (quest)
4/27/2016- 0.781 % I.S (quest)
5/04/2016- 0.652 % I.S.(quest)
5/24/2016- 0.501 % I.S (quest)
6/28/2016-0.534 % I.S (quest)
7/15/2016-0.881 % I.S (quest)
7/22/2016- Bosulif 500mg
7/28/2016- t315i test- Negative
8/22/2016-0.432 % I.S (quest )
11/15/2016-0.325 % I.S (quest)
2/1/2017- .0445% i.s (genoptix)
5/6/2017- .0968% i.s (genoptix)
5/12/2017- .12 % i.s (quest).
6/4/2017- .083% i.s (quest)
6/11/2017- .0295% i.s (genoptix)
8/5/2017- .0501% i.s (genoptix)
11/6/2017- .0270% i.s (genoptix)




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