Hi all. It's been a long time since I've been on this site. I was diagnosed in Feb 2014. I was first put on Sprycel, with bad side effects for me. It was a killer in the beginning (meaning bringing my numbers down quickly), and then it just stopped - numbers didn't move. Then I was put on Tasigna, side effects not as bad, and totally different. Again, number dropped significantly when I first started, and for around a year now I just continue to bounce around, up, down, up, never reached MMR.
My dr. has given me 3 options to think about - 1) Stay on the Tasigna. Physically I usually feel pretty good, a lot more energy than I ever had on Sprycel and again, barely any side effects at this point. However, the chances are very good that I will just continue with the see-saw action and never see MMR. 2) He would put me on Bosutinid. Haven't even had a chance to do any research yet, so I basically know nothing about this med. 3) I could join a clinical trial for ABL001. Just now did minimal research, but looks really good for not only reaching MMR, but eventually being off all meds (which of course sounds wonderful!).
I still have to meet with my doctor to get more information regarding the trial, and always do as much research on my own as I can, but I just wondered if anyone had any thoughts/experiences with either Bosutinid or the ABL001 trial.