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Clonal chromosomal aberrations in Philadelphia negative cells such as monosomy 7 and trisomy 8 may persist for years with no impact on the long term o


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#1 gerry

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Posted 17 October 2017 - 05:17 PM

http://www.cancergen...0345-3/fulltext

#2 scuba

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Posted 17 October 2017 - 07:19 PM

This is good to learn. I am one of those patients having both monosomy 7 (early and now gone) and Trisomy 8 (continues to persist). In both cases, these clones developed post TKI therapy (Sprycel). I continue to have low RBC's - but compensate with extra iron and other blood nutrition (folate). My hemoglobin is in the normal range (barely) as a result.

 

Unfortunately, I won't be running any marathons. 


Diagnosed 11 May 2011 (100% FiSH, 155% PCR)

with b2a2 BCR-ABL fusion transcript coding for the 210kDa BCR-ABL protein

 

Sprycel: 20 mg per day - taken at lights out with Quercetin and/or Magnesium Taurate

6-8 grams Curcumin C3 complex.

 

2015 PCR: < 0.01% (M.D. Anderson scale)

2016 PCR: < 0.01% (M.D. Anderson scale) 

March        2017 PCR:     0.01% (M.D. Anderson scale)

June          2017 PCR:     "undetected"

September 2017 PCR:     "undetected"





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