Clonal chromosomal aberrations in Philadelphia negative cells such as monosomy 7 and trisomy 8 may persist for years with no impact on the long term o
Posted 17 October 2017 - 07:19 PM
This is good to learn. I am one of those patients having both monosomy 7 (early and now gone) and Trisomy 8 (continues to persist). In both cases, these clones developed post TKI therapy (Sprycel). I continue to have low RBC's - but compensate with extra iron and other blood nutrition (folate). My hemoglobin is in the normal range (barely) as a result.
Unfortunately, I won't be running any marathons.
Diagnosed 11 May 2011 (100% FiSH, 155% PCR)
with b2a2 BCR-ABL fusion transcript coding for the 210kDa BCR-ABL protein
Sprycel: 20 mg per day - taken at lights out with Quercetin and/or Magnesium Taurate
6-8 grams Curcumin C3 complex.
2015 PCR: < 0.01% (M.D. Anderson scale)
2016 PCR: < 0.01% (M.D. Anderson scale)
March 2017 PCR: 0.01% (M.D. Anderson scale)
June 2017 PCR: "undetected"
September 2017 PCR: "undetected"
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