Posted 12 October 2017 - 10:14 PM
Lori, testing is done every month when someone is participating in a Stop Study/Stop Trial for the purpose of gathering detailed statistics.
If you aren't participating in a Stop Study how often you test is up to you and your onc..
Testing after one month doesn't usually provide much in the way of very meaningful information.
Testing after two months usually does provide meaningful information and often indicates whether one is heading towards losing MMR.
If you are still undetectable when you test at two months, test again in three more months.
For those losing MMR during Stop Studies, the average is between 3 and 4 months.
Here is a summary of eight forum members who attempted cessation: http://community.lls...ypcru/?p=196277 click on the individual links for more detailed information.
Thanks for adding your history into your Signature.
Good Luck to you,
For the benefit of yourself and others please add your CML history into your Signature
02/2010 Gleevec 400mg
2011 Two weakly positives, PCRU, weakly positive
2012 PCRU, PCRU, PCRU, PCRU
2013 PCRU, PCRU, PCRU, weakly positive
2014 PCRU, PCRU, PCRU, PCRU (12/07 began dose reduction w/each continuing PCRU)
2015 300, 250, 200, 150
2016 100, 50/100, 100, 10/17 TFR
2017 01/17 TFR, 04/18 TFR, 07/18 TFR 0.0012, 08/29 TFR 0.001, 10/17 TFR 0.000
2018 01/16 TFR 0.0004 ... next quarterly PCR 04/17
At the earliest opportunity, and whenever possible, lower your TKI dosage; TKIs are toxic drugs and the less we take longterm the better off we are going to be ... this is especially true for older adults.
In hindsight I should have started my dosage reduction two years earlier; it might have helped minimize some of the longterm cumulative toxic effects of TKIs that I am beset with.
longterm side-effects Peripheral Artery Disease - legs (it's a bitch); continuing shoulder problems, right elbow inflammation. GFR and creatinine vastly improved after stopping Gleevec.
Cumulative Gleevec dosage estimated at 830 grams
Taking Gleevec 400mg an hour after my largest meal of the day helped eliminate the nausea that Gleevec is notorious for.
Trey's CML Blog - Stopping - The Odds - Stop Studies - Discussion Forum Cessation Study
Big PhRMA - Medicare Status - Social Security Status - Deficit/Debt