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peppermint essential oil and tasigna interaction


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#1 Lucas

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Posted 10 September 2017 - 12:07 PM

Hey, guys! Hope everyone's fine here. I always had some eruptions in my scalp and recently my dermatologist suggest me to use a combination of peppermint oil and other herbs in my scalp and it's really getting better. however, i read that peppermint oil is a CYP3A4 inhibitor, i.e., it may cause an increase of tasigna's plasma concentration. My doubt is: even if i have peppermint oil only in my skin, is it possible to have a relevant systemic absorption?



#2 gerry

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Posted 11 September 2017 - 01:36 AM

Usually they are only concerned with pregnant women and the use of oils. It isn't something I would be worried about in regard to a TKI.

#3 carrie

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Posted 11 September 2017 - 03:24 PM

Lucas, So are you worried that the oil will interfere with Tasigna working properly....like how we can't take any Grapefruit products?

I just started Tasigna over a month ago now, and my scalp is dry and itchy. I am trying to figure out what to do. The nurse told me to

take Claritin for the itchy part. I have so many side effects with Tasigna. I do not like this chemo at all.


Diagnosed   2007

On Gleevec for 10 years

Results from 2007-2012 not shown below

International Scale from 2012 until now

Never went to 0

0.166

0.038

1.155

0.789

0.104

0.099

0.701

1.986

1.063

1.799

2.817

1.832

3.449

1.050

1.438

3.376

3.370

3.370

2.580

8.990

4.250

6.176

14.109   Changing to Tasigna 7/7/17

 

7/28/17  800 mgs Tasigna

10/5/17  600 mgs Tasigna (Lots of bad side effects)

10/16/2017    PCR down to 0.141  

1/15/18          PCR down to  0.066   Dose reduction again. Now 400 mgs daily.





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