Posted 04 July 2017 - 12:48 PM
Wow, MooshiDad, you got rescued on the brink!
Re the magical disappearance of the rash: Yup, that's how it goes. And comes. Weird, inexplicable. I had two, maybe three (I mercifully have forgotten) cycles that lasted about a few months each, and then, gone never to come back. (I HOPE!) The only thing I could figure was it had something to do with the natural growth cycle of skin cells. You know how when you get a sunburn, you know it's going to peel in a couple of weeks? There isn't anything you can do to avoid it or hurry it up - the damaged skin cells have to rotate to the surface and slough off, their own sweet time. Anyway, hope the rash doesn't come back for you.
Dx July 2009 on routine physical. WBC 94. Started Gleevec 400 mg Sept 2009. MMR at 2yrs. Side effects (malaise, depression/anxiety, fatigue, nausea, periorbital edema) never improved. Kidney issues developed because of Gleevec. Switched to Sprycel 70 mg in Aug 2011. Above side effects disappeared or improved. Have been MR3.5 - 4.5 ever since. Two untreated pleural effusions followed by one treated by stopping Sprycel Jan 2017. After 9 weeks, PCR showed loss of MMR; re-started Sprycel at 50 mg and in 3 months was back to <0.01% IS. Pleural effusion returned within a couple of months, same as before (moderate, left side only). Stopped Sprycel 50 mg for 12 weeks; pleural effusion resolved. At about a monthoff the drug, PCR was 0.03; at 11 weeks it was 2.06 - lost CCyR? Have returned to 50 mg Sprycel for 3 weeks, intending to reduce to 20 mg going forward.