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[gerry]

Since the advent of tyrosine kinase inhibitors (TKIs), chronic myeloid leukemia (CML) has been transformed from a disease that was usually fatal into one in which patients have a close-to-normal life expectancy. In some cases, the response to treatment is sufficiently prolonged and deep that patients may be able to discontinue their medication. Is this a good idea? In this month's Counterpoints, Drs Nicholas Short and Elias Jabbour argue for the continued treatment of CML, whereas Drs Gabriel Etienne and François-Xavier Mahon make the case for treatment discontinuation.

http://www.hematolog...e-indefinitely/

[gerry]

ASCO - US perspective of TKI therapy discontinuation in CML patients


http://www.cmladvoca...in-cml-patients