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TKI Time of Day Dosing re. Side effects

tki side effects

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#1 blueheron

blueheron

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Posted 25 June 2017 - 08:18 AM

Is there any correlation between side effects and dosing time? Morning vs. Bedtime? I could see how moving the drug through an active awake system might limit side effects vs. slower overall metabolism while sleeping, but have no idea if this is the case. Is there any data on this? Thanks CMLers, hope your day is a good one.


DX 6/2013

Sprycel 100mg

CCR 3/2015

MMR 2/2016

<.01 IS 10/16 hopkins didn't report actual percentage

.007 IS 6/2017

<.01 12/2017 again no actual percentage but didn't see the report myself yet





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