I take Tasigna and the package says it must be stored at 68 - 77 degrees fahrenheit with excursions permitted between 59 and 86. It doesn't say how long excursions can be. My medicine comes overnight from Briova specialty pharmacy and there is no special packaging to insure adherence to the temperature guidelines. I questioned Briova about this and they sent me a letter from Novartis (manufacturer of tasigna) marked "For informational purposes only". The letter said that no significant change in the assay of Tasigna capsules or dissolution results were observed after 6 months of storage at -4 degrees F or after 6 months of storage at 104 degrees F or after 3 months of storage at 122 degrees F. These ranges are a huge difference from what the official Novartis literature says, but my insurance company says that this informational purposes only letter is why they do not provide special packaging when they ship it.
It is already starting to get hot in Florida where I live. Even with overnight delivery, the medicine will be exposed to temperatures in the 90's and maybe even the 100's once we get into June, July, August and Spetember. Should I be concerned? Do the other primary TKI's have similar temp ranges for storage? Do others get their medicine in protective packaging designed to keep it at the correct temp range?
This is all very baffling to me, but I want to make sure my medicine is at full efficacy when I get it and take it.