http://www.cancernet...ny-cml-patients
"The notion that TKIs may never be stopped was successfully challenged in imatinib-treated patients with deep and sustained molecular responses," wrote study authors led by Delphine Rea, MD, PhD, of Hôpital Saint-Louis in Paris. Second-generation TKIs induce higher rates of deep responses and a more rapid decline in BCR-ABL1 transcript levels compared with imatinib in newly diagnosed patients. "These data suggest that the use of dasatinib or nilotinib may increase opportunities to attempt treatment cessation in comparison with imatinib."
